Hemin-functionalised conducting polymer as a unique host matrix for the electrochemical synthesis of benzothiazole derivatives: A sustainable approach

Abstract

An electrocatalyst based on the non-toxic and biologically derived metalloporphyrin hemin, immobilized on poly 3,4-diaminobenzoic acid (PDABA) was utilized for the sustainable electrochemical synthesis of benzothiazole derivatives. Electrochemical and topographical attributes of the electrocatalyst were analyzed critically using a ferricyanide probe, electrochemical impedance spectroscopy (EIS), X-ray photoelectron spectroscopy (XPS), optical profilometry, FTIR, and FE-SEM techniques. The modified electrode was employed for the electrochemical synthesis of benzothiazole derivatives using various aromatic aldehydes and 2-aminothiophenol. The reactions were performed in a three-electrode system, at oxidation potentials derived from cyclic voltametric elucidations, using lithium perchlorate as the supporting electrolyte and ethanol as the solvent. The products obtained were crystallized, purified and confirmed with the help of ¹H-NMR spectroscopy, showing yields ranging from 78-92 %. The hemin based heterogenous electrocatalyst enhances the efficacy of the reaction by reducing reaction time, and negating tedious work-up procedures, thereby making the method highly facile and environmentally benign.