A flavonol-based fluorescent probe for N2H4 detection and its applications in natural environmental samples

IF 4.6 2区化学 Q1 SPECTROSCOPY

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Pub Date : 2025-09-29 DOI:10.1016/j.saa.2025.126982

Yu Wang, Licheng Li, Zhonglong Wang

{"title":"A flavonol-based fluorescent probe for N2H4 detection and its applications in natural environmental samples","authors":"Yu Wang, Licheng Li, Zhonglong Wang","doi":"10.1016/j.saa.2025.126982","DOIUrl":null,"url":null,"abstract":"<div><div>Hydrazine possesses a diverse range of applications and exhibits favorable water solubility, which can lead to contamination and toxicity in both the natural environment and human beings due to improper handling. Therefore, it is particularly important to establish a reliable and accurate analytical method for detecting hydrazine. In this study, we designed and synthesized a flavonoid-based fluorescent probe DP-N2H4 that specifically tailored for hydrazine detection, thoroughly investigating its spectral properties and response mechanism. DP-N2H4 demonstrated exceptional selectivity towards N2H4 with an impressively low detection limit of 0.468 μM, showcasing remarkable sensitivity towards N2H4 as well. Furthermore, our findings demonstrated that the probe effectively recognized hydrazine in various environmental and biological samples including ambient water, soil, and living cells.</div></div>","PeriodicalId":433,"journal":{"name":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","volume":"347 ","pages":"Article 126982"},"PeriodicalIF":4.6000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1386142525012892","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"SPECTROSCOPY","Score":null,"Total":0}

引用次数: 0

Abstract

Hydrazine possesses a diverse range of applications and exhibits favorable water solubility, which can lead to contamination and toxicity in both the natural environment and human beings due to improper handling. Therefore, it is particularly important to establish a reliable and accurate analytical method for detecting hydrazine. In this study, we designed and synthesized a flavonoid-based fluorescent probe DP-N₂H₄ that specifically tailored for hydrazine detection, thoroughly investigating its spectral properties and response mechanism. DP-N₂H₄ demonstrated exceptional selectivity towards N₂H₄ with an impressively low detection limit of 0.468 μM, showcasing remarkable sensitivity towards N₂H₄ as well. Furthermore, our findings demonstrated that the probe effectively recognized hydrazine in various environmental and biological samples including ambient water, soil, and living cells.

Abstract Image

查看原文本刊更多论文

基于黄酮醇的N2H4荧光探针及其在自然环境样品中的应用

联氨具有广泛的用途和良好的水溶性，但如果处理不当，会对自然环境和人体造成污染和毒性。因此，建立一种可靠、准确的联氨检测方法显得尤为重要。在本研究中，我们设计并合成了一种专门用于肼检测的类黄酮荧光探针DP-N2H4，并对其光谱性质和响应机制进行了深入研究。DP-N2H4对N2H4具有良好的选择性，检测限低至0.468 μM，对N2H4也具有良好的灵敏度。此外，我们的研究结果表明，探针可以有效识别各种环境和生物样品中的肼，包括环境水、土壤和活细胞。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 物理-光谱学

CiteScore

8.40

自引率

11.40%

发文量

1364

审稿时长

40 days

期刊介绍： Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (SAA) is an interdisciplinary journal which spans from basic to applied aspects of optical spectroscopy in chemistry, medicine, biology, and materials science. The journal publishes original scientific papers that feature high-quality spectroscopic data and analysis. From the broad range of optical spectroscopies, the emphasis is on electronic, vibrational or rotational spectra of molecules, rather than on spectroscopy based on magnetic moments. Criteria for publication in SAA are novelty, uniqueness, and outstanding quality. Routine applications of spectroscopic techniques and computational methods are not appropriate. Topics of particular interest of Spectrochimica Acta Part A include, but are not limited to: Spectroscopy and dynamics of bioanalytical, biomedical, environmental, and atmospheric sciences, Novel experimental techniques or instrumentation for molecular spectroscopy, Novel theoretical and computational methods, Novel applications in photochemistry and photobiology, Novel interpretational approaches as well as advances in data analysis based on electronic or vibrational spectroscopy.