Biomechanical evaluation of shape-optimized CAD/CAM magnesium plates for mandibular reconstruction

IF 3.5 2区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of the Mechanical Behavior of Biomedical Materials Pub Date : 2025-10-06 DOI:10.1016/j.jmbbm.2025.107222

Philipp Ruf , Kilian Richthofer , Vincenzo Orassi , Claudius Steffen , Georg N. Duda , Max Heiland , Sara Checa , Carsten Rendenbach

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引用次数: 0

Abstract

Magnesium CAD/CAM miniplates are a promising alternative to titanium plates for mandibular reconstruction. However, gas formation is an inherent part of the magnesium degradation process, and thus, the quantity of magnesium used in fixation scenarios should be limited. Previous studies described several strategies to limit material volume, such as plate thickness reduction and shape-optimization. In particular, shape-optimization has been described as a strategy to limit material volume while maintaining mechanical integrity.

In consequence, the present study compared a shape-optimized CAD/CAM magnesium miniplate with standard CAD/CAM magnesium miniplates of varying thicknesses using a biomechanical finite element model. A single-segment mandibular reconstruction was chosen as the investigative scenario, evaluated under different biting tasks to assess the different plate shapes.

The shape-optimized magnesium plate demonstrated similar primary fixation stability compared to standard CAD/CAM magnesium miniplates, despite having reduced plate material and surface area. Shape optimization could help minimize magnesium volume and surface area to mitigate the issue of gas formation during the degradation process in vivo while maintaining biomechanical performance comparable to common CAD/CAM miniplates.

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形状优化CAD/CAM镁板下颌骨重建的生物力学评价

镁CAD/CAM微型钢板是一种很有前途的下颌重建钛板替代品。然而，气体的形成是镁降解过程的固有部分，因此，在固定场景中使用的镁的数量应该受到限制。先前的研究描述了几种限制材料体积的策略，如板厚度减少和形状优化。特别是，形状优化被描述为一种在保持机械完整性的同时限制材料体积的策略。因此，本研究使用生物力学有限元模型将形状优化的CAD/CAM微型镁板与不同厚度的标准CAD/CAM微型镁板进行了比较。选择单节段下颌骨重建作为研究场景，在不同的咬合任务下评估不同的钢板形状。与标准CAD/CAM镁微型板相比，形状优化的镁板显示出相似的初级固定稳定性，尽管减少了板材料和表面积。形状优化可以帮助减少镁的体积和表面积，以减轻体内降解过程中气体形成的问题，同时保持与普通CAD/CAM微型板相当的生物力学性能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Mechanical Behavior of Biomedical Materials 工程技术-材料科学：生物材料

CiteScore

7.20

自引率

7.70%

发文量

505

审稿时长

46 days

期刊介绍： The Journal of the Mechanical Behavior of Biomedical Materials is concerned with the mechanical deformation, damage and failure under applied forces, of biological material (at the tissue, cellular and molecular levels) and of biomaterials, i.e. those materials which are designed to mimic or replace biological materials. The primary focus of the journal is the synthesis of materials science, biology, and medical and dental science. Reports of fundamental scientific investigations are welcome, as are articles concerned with the practical application of materials in medical devices. Both experimental and theoretical work is of interest; theoretical papers will normally include comparison of predictions with experimental data, though we recognize that this may not always be appropriate. The journal also publishes technical notes concerned with emerging experimental or theoretical techniques, letters to the editor and, by invitation, review articles and papers describing existing techniques for the benefit of an interdisciplinary readership.