Cannabis use disorder risks among Medicaid enrollees with comorbid psychiatric illnesses: 2012–2021

IF 3.6 2区医学 Q1 PSYCHIATRY

Drug and alcohol dependence Pub Date : 2025-10-09 DOI:10.1016/j.drugalcdep.2025.112915

Jialin Hou , Jeffery C. Talbert , Jayani Jayawardhana

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引用次数: 0

Abstract

Objectives

To examine trends in prevalence of cannabis use disorder (CUD) among Medicaid enrollees with and without comorbid psychiatric illnesses - depression, anxiety, or insomnia - overall and by sex and age subgroups.

Methods

Medicaid enrollees aged 18–64 in the Merative Multi-state Claims and Encounters Database with diagnoses of CUD and comorbid psychiatric illnesses - depression, anxiety, or insomnia - from 2012 to 2021 were examined using a multi-variate logit regression adjusting for sex, age, and race. Additionally, CUD and comorbid chronic pain diagnosis for the same population were examined as a comparison. We estimated the changes in the prevalence of CUD among enrollees with and without depression, anxiety, or insomnia.

Results

From 2012–2021, the predicted prevalence of CUD among enrollees with depression, anxiety, and insomnia as a comorbidity increased by 1.04 (p < 0.001), 1.36 (p < 0.001), 1.64 (p < 0.001) times compared to the enrollees without those comorbidities, respectively, while the predicted prevalence of CUD among enrollees with chronic pain reduced by 0.90 (p < 0.001) times compared to those without chronic pain. Relative increases in the predicted prevalence of CUD were higher among females and those aged 35–64 with anxiety and depression, and among males and those aged 21–34 with insomnia.

Conclusions

Medicaid enrollees with depression, anxiety, or insomnia were increasingly more likely to experience CUD diagnoses for the past decade compared to those without the condition. Further research is needed to understand the mechanism between cannabis use and psychiatric illnesses and curb the rising CUD associated with comorbid psychiatric illnesses.

查看原文本刊更多论文

大麻使用障碍风险在医疗补助计划参保者与共病精神疾病：2012-2021

目的研究有或无共病精神疾病（抑郁、焦虑或失眠）的医疗补助参保者中大麻使用障碍（CUD）的流行趋势，并按性别和年龄分组。方法对2012年至2021年在Merative多州索赔和遭遇数据库中诊断为CUD和共病精神疾病（抑郁、焦虑或失眠）的18-64岁医疗补助参保者进行多变量logit回归，调整性别、年龄和种族。此外，对同一人群的CUD和共病慢性疼痛诊断进行了比较。我们估计了伴有和不伴有抑郁、焦虑或失眠的受试者中CUD患病率的变化。结果2012-2021年，伴有抑郁、焦虑和失眠共病的参保者的CUD预测患病率比无这些共病参保者分别增加1.04 （p < 0.001）、1.36 （p < 0.001）、1.64 （p < 0.001）倍，而伴有慢性疼痛参保者的CUD预测患病率比无慢性疼痛参保者减少0.90 （p < 0.001）倍。伴有焦虑和抑郁的女性和35-64岁人群，以及伴有失眠症的男性和21-34岁人群中，预测CUD患病率的相对增幅较高。结论：在过去的十年中，与那些没有抑郁、焦虑或失眠的人相比，有抑郁、焦虑或失眠的医疗补助参保者更有可能被诊断为CUD。需要进一步的研究来了解大麻使用与精神疾病之间的机制，并遏制与共病精神疾病相关的CUD上升。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drug and alcohol dependence 医学-精神病学

CiteScore

7.40

自引率

7.10%

发文量

409

审稿时长

41 days

期刊介绍： Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.