Impact of Vomer Flap on Nutritional Status in Infants With Cleft Lip and Palate: A Multicenter Retrospective Cohort Study.

IF 1.3 4区 医学 Q2 Dentistry
Sofia Bachini, Robin Delnoij, Edith Visser, Chantal Moues-Vink, Corstiaan C Breugem
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Abstract

ObjectiveTo determine the effect of early hard palate closure by means of a Vomer flap (VF) on the nutritional status of children with cleft lip and palate.DesignMulticenter retrospective cohort study.SettingThree referral centers for oral clefts.Patients, ParticipantsNonsyndromic children with UCLP or BCLP.Interventions: Early hard palate closure with a VF at cheiloplasty around 3 months versus isolated cheiloplasty, both followed by palatoplasty around 9 to 10 months.Main Outcome Measure(s)Anthropometric measures (weight and height) and related weight-for-age and height-for-age Z-scores at the time of cheiloplasty and palatoplasty.ResultsBetween 2012 and 2024, 122 children with UCLP or BCLP underwent cleft repair surgery. Median age at cheiloplasty was 111 (99-126) days and 304 (284-342) at palatoplasty. In 60% of them (n = 73), a VF was performed simultaneously with cheiloplasty. Weight increase between cheiloplasty and palatoplasty was slightly more for the VF group compared to the control group by 0.24 kg (SE = 0.15, P = .13). No height difference was measured between the groups (P = .80). Z-score variation between cheiloplasty and palatoplasty was significantly different for all study groups, indicating a strong normalization of the growth curve after cheiloplasty (P < .001).ConclusionsEarly hard palate closure using a VF may favor growth in children with cleft lip and palate. The deviation from the normative growth curve of infants decreases significantly between cheiloplasty and palatoplasty, regardless of whether a VF was performed.

腭瓣对唇腭裂婴儿营养状况的影响:一项多中心回顾性队列研究。
目的探讨早期腭瓣封闭对唇腭裂患儿营养状况的影响。设计多中心回顾性队列研究。三家唇腭裂转诊中心。患者、参与者:无综合征的UCLP或BCLP患儿。干预措施:腭裂成形术3个月左右早期硬腭闭合与VF,与孤立的腭裂成形术相比,两者都在9至10个月左右进行腭裂成形术。主要观察指标:颧骨成形术和腭成形术时的人体测量值(体重和身高)以及相关的年龄体重和年龄身高z分数。结果2012年至2024年间,122名患有UCLP或BCLP的儿童接受了腭裂修复手术。唇腭裂成形术的中位年龄为111(99-126)天,腭裂成形术的中位年龄为304(284-342)天。其中60% (n = 73)的患者在吻合器成形术的同时进行了VF。与对照组相比,VF组在唇腭裂成形术和唇腭裂成形术之间的体重增加了0.24 kg (SE = 0.15, P = 0.13)。各组间无身高差异(P = 0.80)。在所有研究组中,唇瓣成形术和腭瓣成形术之间的Z-score差异有显著性差异,表明唇瓣成形术后的生长曲线具有很强的规整性(P)。无论是否进行VF,在唇腭裂成形术和唇腭裂成形术之间,婴儿与标准生长曲线的偏差显著降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Cleft Palate-Craniofacial Journal
Cleft Palate-Craniofacial Journal DENTISTRY, ORAL SURGERY & MEDICINE-SURGERY
CiteScore
2.20
自引率
36.40%
发文量
0
审稿时长
4-8 weeks
期刊介绍: The Cleft Palate-Craniofacial Journal (CPCJ) is the premiere peer-reviewed, interdisciplinary, international journal dedicated to current research on etiology, prevention, diagnosis, and treatment in all areas pertaining to craniofacial anomalies. CPCJ reports on basic science and clinical research aimed at better elucidating the pathogenesis, pathology, and optimal methods of treatment of cleft and craniofacial anomalies. The journal strives to foster communication and cooperation among professionals from all specialties.
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