Sella Turcica Dimension and Shape in Trisomy 21: A CT Examination.

IF 1 4区医学 Q3 SURGERY

Journal of Craniofacial Surgery Pub Date : 2025-10-06 DOI:10.1097/SCS.0000000000012029

Sibel Özalp, Mehmet Z Erdem, Abdulaziz Yalinkiliç, Abdulmutalip Karaaslanli, Burhan Beger, Bülent Sönmez, Bilal Arslan, Hadice Uçar, Turan Koç, Mitat Selçuk Bozhöyük, Orhan Beger

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引用次数: 0

Abstract

Objective: The aim of the study was to compare the morphologic features of the sella turcica (ST) in patients with trisomy 21 (T21) with a control group.

Methods: This retrospective study contained computed tomography images of 45 T21s and 53 controls. Of 45 T21s patients aged 10.31±3.92 years, 21 were females and 24 were males. Of 53 controls aged 12.11±3.91 years, 26 were females and 27 were males. ST shape and size were noted.

Results: T21 subjects had statistically greater ST length (P<0.001), anterior height (P=0.004), middle height (P=0.001) and width (P<0.001) than controls, but similar diameter (P=0.098) and posterior height (P=0.097). Six types related to Axelsson classification were noted in T21s with the following frequencies: normal ST (42.2%)>oblique anterior wall (28.9%)>pyramidal shape of the dorsum sellae (15.6%)>double contour of the floor (6.7%)>irregularity (4.4%)>ST bridge (2.2%). Four types regarding this classification were noted in controls with the following frequencies: normal ST (41.5%)>pyramidal shape of the dorsum sellae (34%)>oblique anterior wall (22.6%)>double contour of the floor (1.9%). Three types related to Camp classification were noted in T21s with the following frequencies: round (44.4%)>oval (33.4%)>flattened (22.2%). Three types regarding this classification were noted in controls with the following frequencies: round (49.1%)>oval (37.7%)>flattened (13.2%).

Conclusion: Our CT study displays that ST size is affected by T21. However, the ST shape does not correlate with T21.

查看原文本刊更多论文

21三体蝶鞍的尺寸和形状：CT检查。

目的：比较21三体（T21）患者与对照组蝶鞍（ST）的形态学特征。方法：本回顾性研究包含45例t21患者和53例对照者的计算机断层图像。45例t21患者（10.31±3.92岁）中，女性21例，男性24例。对照组53例，年龄12.11±3.91岁，女性26例，男性27例。记录ST的形状和大小。结果：T21组患者ST段长度(前壁斜突（28.9%）、鞍背锥体（15.6%）、底双等高线（6.7%）、底不规则（4.4%）、ST桥（2.2%）均有统计学差异。在对照组中有四种类型，频率如下：正常ST型（41.5%）、>鞍背锥体型（34%）、>斜前壁型（22.6%）、>双底轮廓型（1.9%）。t21有3种与Camp分类相关的类型，频率为圆形（44.4%）、椭圆形（33.4%）、扁平（22.2%）。在对照组中，这种分类有三种类型，频率如下：圆形（49.1%）、椭圆形（37.7%）、扁平（13.2%）。结论：我们的CT研究显示ST的大小受T21的影响。然而，ST形状与T21无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Craniofacial Surgery 医学-外科

CiteScore

1.70

自引率

11.10%

发文量

968

审稿时长

1.5 months

期刊介绍： The Journal of Craniofacial Surgery serves as a forum of communication for all those involved in craniofacial surgery, maxillofacial surgery and pediatric plastic surgery. Coverage ranges from practical aspects of craniofacial surgery to the basic science that underlies surgical practice. The journal publishes original articles, scientific reviews, editorials and invited commentary, abstracts and selected articles from international journals, and occasional international bibliographies in craniofacial surgery.