{"title":"Effectiveness of Nursing Care Intervention Among Patients With Hepatocellular Carcinoma Undergoing Surgery: A Systematic Review and Meta-Analysis","authors":"Wei Geng, Danling Wang, Xinwei Feng","doi":"10.1111/ijn.70065","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Aim</h3>\n \n <p>This meta-analysis examines the effectiveness of nursing interventions on various outcomes, including mortality, postoperative complications, quality of life (QoL), anxiety, depression and pain in HCC patients undergoing surgery.</p>\n </section>\n \n <section>\n \n <h3> Background</h3>\n \n <p>Hepatocellular carcinoma (HCC) is a prevalent liver malignancy often requiring surgical intervention. Postoperative outcomes in HCC patients are heavily influenced by perioperative management, with nursing interventions playing a critical role in improving recovery, minimizing complications and enhancing QoL.</p>\n </section>\n \n <section>\n \n <h3> Design</h3>\n \n <p>Systematic review and meta-analysis.</p>\n </section>\n \n <section>\n \n <h3> Review Methods</h3>\n \n <p>This review was conducted following PRISMA guidelines, evaluating studies on nursing interventions in surgical HCC patients. Databases were searched for studies reporting clinical and psychological outcomes, with eligible studies pooled using random-effects models. Heterogeneity, sensitivity analyses and publication bias assessments were performed to ensure robustness.</p>\n </section>\n \n <section>\n \n <h3> Result</h3>\n \n <p>Twenty-seven studies were analysed. Nursing interventions significantly reduced postoperative complications (OR 0.23; 95% CI: 0.17–0.31) and shortened hospital stay (WMD −5.92 days; 95% CI: −7.76 to −4.08). Additionally, significant improvements were observed in QoL (SMD 2.00; 95% CI: 0.74–3.27), anxiety (SMD −3.42; 95% CI: −5.95 to −0.89) and depression (SMD −3.70; 95% CI: −6.52 to −0.88). Pain levels were significantly reduced (WMD −2.02; 95% CI: −3.03 to −1.02), while nursing satisfaction was enhanced (OR 4.80; 95% CI: 2.42–9.51). Mortality did not show significant differences between groups.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Nursing interventions significantly enhance postoperative outcomes in HCC patients by reducing complications, improving QoL and alleviating psychological distress. These findings support integrating comprehensive nursing protocols into postoperative HCC care, emphasizing both physical and mental health.</p>\n </section>\n </div>","PeriodicalId":14223,"journal":{"name":"International Journal of Nursing Practice","volume":"31 5","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Nursing Practice","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/ijn.70065","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NURSING","Score":null,"Total":0}
引用次数: 0
Abstract
Aim
This meta-analysis examines the effectiveness of nursing interventions on various outcomes, including mortality, postoperative complications, quality of life (QoL), anxiety, depression and pain in HCC patients undergoing surgery.
Background
Hepatocellular carcinoma (HCC) is a prevalent liver malignancy often requiring surgical intervention. Postoperative outcomes in HCC patients are heavily influenced by perioperative management, with nursing interventions playing a critical role in improving recovery, minimizing complications and enhancing QoL.
Design
Systematic review and meta-analysis.
Review Methods
This review was conducted following PRISMA guidelines, evaluating studies on nursing interventions in surgical HCC patients. Databases were searched for studies reporting clinical and psychological outcomes, with eligible studies pooled using random-effects models. Heterogeneity, sensitivity analyses and publication bias assessments were performed to ensure robustness.
Result
Twenty-seven studies were analysed. Nursing interventions significantly reduced postoperative complications (OR 0.23; 95% CI: 0.17–0.31) and shortened hospital stay (WMD −5.92 days; 95% CI: −7.76 to −4.08). Additionally, significant improvements were observed in QoL (SMD 2.00; 95% CI: 0.74–3.27), anxiety (SMD −3.42; 95% CI: −5.95 to −0.89) and depression (SMD −3.70; 95% CI: −6.52 to −0.88). Pain levels were significantly reduced (WMD −2.02; 95% CI: −3.03 to −1.02), while nursing satisfaction was enhanced (OR 4.80; 95% CI: 2.42–9.51). Mortality did not show significant differences between groups.
Conclusion
Nursing interventions significantly enhance postoperative outcomes in HCC patients by reducing complications, improving QoL and alleviating psychological distress. These findings support integrating comprehensive nursing protocols into postoperative HCC care, emphasizing both physical and mental health.
期刊介绍:
International Journal of Nursing Practice is a fully refereed journal that publishes original scholarly work that advances the international understanding and development of nursing, both as a profession and as an academic discipline. The Journal focuses on research papers and professional discussion papers that have a sound scientific, theoretical or philosophical base. Preference is given to high-quality papers written in a way that renders them accessible to a wide audience without compromising quality. The primary criteria for acceptance are excellence, relevance and clarity. All articles are peer-reviewed by at least two researchers expert in the field of the submitted paper.