Dietary nucleotides supplementation enhances the growth and immune responses of the giant freshwater prawn, Macrobrachium rosenbergii (De Man, 1879).

IF 1.5 Q3 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Journal of Advanced Veterinary and Animal Research Pub Date : 2025-06-25 eCollection Date: 2025-06-01 DOI:10.5455/javar.2025.l932

Belal Hossen, Rokonuzzaman Kibria, Sakib Tahmid Rishan, Muhammad Tofazzal Hossain, Samsul Alam

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Abstract

Objective: The study aimed to assess the impact of dietary nucleotide (NT) supplementation on the growth performance and immune response of juvenile Macrobrachium rosenbergii.

Materials and methods: A commercial diet was supplemented with 0.0% (control), 0.10% (T1), 0.15% (T2), and 0.20% (T3) NT for the study. A total of 132 juvenile prawns (0.78 ± 0.03 gm) were randomly distributed into four groups, each having three replicates. Following the 75-day feeding trial, the experimental prawns were exposed to Aeromonas veronii at 8.35 × 10⁵ colony forming unit (cfu)/ml for 7 days through a bath treatment.

Results: The growth parameters and survival rate were significantly higher (p < 0.05) in NT-supplemented prawns. Immune-related parameters, e.g., total hemocyte count (THC), hemolymph protein, albumin, globulin, superoxide dismutase, and catalase activity, were also significantly higher (p < 0.05) in NT-supplemented prawns. The challenge of prawn with A. veronii resulted in a significant reduction (p < 0.05) in THC and other biochemical parameters of hemolymph and caused mortality in all the experimental groups. However, significantly higher survival (p < 0.05) against the A. veronii challenge was found in NT-supplemented prawns.

Conclusion: It can be concluded that dietary NTs should be supplemented at 0.15%-0.2% to enhance the growth, immunity, and resistance of juvenile M. rosenbergii against A. veronii.

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在饲料中添加核苷酸可以促进罗氏沼虾的生长和免疫反应（De Man, 1879）。

目的：研究饲料中添加核苷酸（NT）对罗氏沼虾（Macrobrachium rosenbergii）幼鱼生长性能和免疫应答的影响。材料与方法：在商品饲粮中添加0.0%（对照）、0.10% （T1）、0.15% （T2）和0.20% (T3) NT。选取132尾（0.78±0.03 gm）对虾，随机分为4组，每组3个重复。75 d饲喂试验后，通过水浴处理，以8.35 × 105菌落形成单位(cfu)/ml的剂量暴露于试验对虾7 d。结果：添加nt的对虾的生长参数和成活率显著提高（p < 0.05）。添加nt的对虾的免疫相关参数，如总血细胞计数（THC）、血淋巴蛋白、白蛋白、球蛋白、超氧化物歧化酶和过氧化氢酶活性也显著升高（p < 0.05）。凡氏弧菌攻毒后，各试验组对虾血淋巴THC等生化指标均显著降低（p < 0.05），并导致死亡。然而，添加nt的对虾对维氏弧菌的存活率显著提高（p < 0.05）。结论：饲粮中添加0.15% ~ 0.2%的NTs可促进罗氏沼虾幼虾的生长、免疫和对维氏单胞杆菌的抗性。

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来源期刊

Journal of Advanced Veterinary and Animal Research Veterinary-Veterinary (all)

CiteScore

2.70

自引率

7.10%

发文量

审稿时长

6 weeks

期刊介绍： Journal of Advanced Veterinary and Animal Research (JAVAR) - is an open access, international, peer-reviewed, quarterly, highly-indexed scientific journal publishing original research findings and reviews on all aspects of veterinary and animal sciences. Basic and applied researches on- - Anatomy & histology - Animal health economics - Animal nutrition - Animal reproduction - Animal science - Antimicrobial resistance (AMR) - Biochemistry - Biotechnology - Dairy science - Epidemiology - Food hygiene and technology - Genetics and breeding - Immunology - Microbiology - Parasitology - Pathology - Pharmacology & toxicology - Physiology - Poultry science - Preventive veterinary medicine - Public health - Surgery & obstetrics - Veterinary extension studies - Wildlife & aquatic medicine - Zoo animal medicine.