Global, regional, and national burden of mental disorders and substance use disorders in older adults from 1990 to 2021: a systematic analysis and future trend prediction study.

IF 3.2 3区 医学 Q2 PSYCHIATRY
Frontiers in Psychiatry Pub Date : 2025-09-24 eCollection Date: 2025-01-01 DOI:10.3389/fpsyt.2025.1638646
Yitian Gao, Wanqiong Zhou, Qiuyi Wang, Qianyi Zhai, Lanshu Zhou
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Abstract

Introduction: As the global population ages, mental health has become a major public health issue affecting healthy aging. To estimate the burden, trends, and inequalities of mental disorders and substance use disorders (SUDs) among older adults aged ≥60 years at the global, regional, and national levels from 1990 to 2021.

Methods: Data from the Global Burden of Disease Study 2021. The study focused on the burden of mental health conditions, analyzing mental disorders and SUDs prevalence, years lived with disability (YLDs), and average annual percentage change (AAPC), encompassing eight age groups (60-64 years, 65-69 years, 70-74 years, 75-79 years, 80-84 years, 85-89 years, 90-94 years, ≥95 years) for both men and women.

Results: Globally in 2021, 1.09 billion individuals aged ≥60 years included 161.3 million (14.8%) with mental disorders and 19.2 million (1.8%) with SUDs. Mental disorders accounted for 22.8 million YLDs versus 2.10 million from SUDs in this population. From 1990 to 2021, age standardized prevalence of mental disorders increased by 3.7%, while SUDs declined by 8.7%, with lower SDI levels correlating with higher YLDs burdens overall. Over the next fifteen years, projections indicating stagnant trends in SUDs alongside slight declines in mental disorders highlight persistent unmet needs.

Discussion: Global population aging demands heightened prioritization of mental healthcare for older adults. Today, mental and substance use disorders persist as major contributors to disease burden in this population. Our findings call for equitable mental resource allocation, age-adapted diagnostic tools, and policies targeting late-life psychosocial vulnerabilities.

1990年至2021年全球、区域和国家老年人精神障碍和物质使用障碍负担:系统分析和未来趋势预测研究
引言:随着全球人口老龄化,心理健康已成为影响健康老龄化的重大公共卫生问题。估计1990年至2021年全球、区域和国家各级60岁以上老年人精神障碍和物质使用障碍(sud)的负担、趋势和不平等。方法:数据来自2021年全球疾病负担研究。该研究侧重于心理健康状况的负担,分析了男性和女性的精神障碍和sud患病率、残疾生活年数(YLDs)和平均年百分比变化(AAPC),涵盖了8个年龄组(60-64岁、65-69岁、70-74岁、75-79岁、80-84岁、85-89岁、90-94岁、≥95岁)。结果:2021年,全球10.9亿≥60岁的人,其中1.613亿(14.8%)患有精神障碍,1920万(1.8%)患有sud。在这一人群中,精神障碍患者占2280万,而猝死患者占210万。从1990年到2021年,年龄标准化精神障碍患病率增加了3.7%,而sud下降了8.7%,总体而言,SDI水平较低与YLDs负担较高相关。在今后15年里,预测表明,sud的趋势停滞不前,同时精神障碍略有下降,这突出了持续未满足的需求。讨论:全球人口老龄化要求对老年人的精神卫生保健给予高度重视。今天,精神和物质使用障碍仍然是造成这一人群疾病负担的主要因素。我们的研究结果呼吁公平的精神资源分配,适合年龄的诊断工具,以及针对老年社会心理脆弱性的政策。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Frontiers in Psychiatry
Frontiers in Psychiatry Medicine-Psychiatry and Mental Health
CiteScore
6.20
自引率
8.50%
发文量
2813
审稿时长
14 weeks
期刊介绍: Frontiers in Psychiatry publishes rigorously peer-reviewed research across a wide spectrum of translational, basic and clinical research. Field Chief Editor Stefan Borgwardt at the University of Basel is supported by an outstanding Editorial Board of international researchers. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide. The journal''s mission is to use translational approaches to improve therapeutic options for mental illness and consequently to improve patient treatment outcomes.
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