Association between suicidal behaviour in pregnant women and pregnancy and fetal outcomes: A systematic review and meta-analysis.

IF 2.7 3区医学 Q2 PSYCHIATRY

Archives of Women's Mental Health Pub Date : 2025-10-10 DOI:10.1007/s00737-025-01623-9

Maitry Sukhadeve, Farhan Farooque Khan, Nishaant Ramasamy, Akanksha P Dani, Swapnajeet Sahoo, Prachi Dixit, Aravind P Gandhi

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引用次数: 0

Abstract

Purpose: Suicidal behavior during pregnancy, including ideation, planning, and attempts, represents a significant but under-researched public health concern linked to adverse maternal and fetal outcomes such as preterm labor, low birth weight, and stillbirth. This systematic review and meta-analysis (SRMA) aimed to synthesize evidence on the association between suicidal behavior during pregnancy and feto-maternal outcomes, addressing existing gaps in the literature.

Materials and methods: The SRMA, following PRISMA 2020 guidelines, included observational studies that reported maternal and fetal outcomes among pregnant women exhibiting suicidal behaviour (suicidal ideation, planning, or attempts). Four databases (PubMed, Embase, Web of Science, and Cochrane) were searched up to April 30, 2025, and 18 studies were included. Risk of bias assessment was done using the Newcastle-Ottawa scale. Data were analysed using random-effects models to calculate pooled relative risks (RRs) and 95% confidence intervals (CIs).

Results: From the 18 studies included for the SRMA, a total of 30749705 participants were analysed, with 6557 in the suicidal behaviour group. Suicidal behaviour significantly increased the risk of preterm labor (RR = 1.78, 95% CI: 1.7-1.86), preterm birth (RR = 1.40, 95% CI: 1.26-1.55), fetal anomaly (RR = 1.84, 95% CI: 1.22-2.77) and Low Birth Weight (RR = 1.83, 95% CI: 1.67-2.02), with no heterogeneity observed (I² = 0%). Stillbirth risk was markedly elevated (RR = 11.92, 95% CI: 10.32-13.77). Other outcomes, such as placental abruption and postpartum hemorrhage, also demonstrated increased risks. All the outcomes had a low to very low certainty of evidence.

Conclusion: Suicidal behaviour during pregnancy poses significant risks to maternal and fetal health, emphasizing the need for early identification and interventions. Addressing maternal mental health must be prioritized in prenatal care to improve outcomes for both mother and child. Others: The protocol was registered in the PROSPERO (ID: CRD42024539860).

查看原文本刊更多论文

孕妇自杀行为与妊娠和胎儿结局之间的关系：一项系统回顾和荟萃分析。

目的：怀孕期间的自杀行为，包括构思、计划和尝试，是一个重要但研究不足的公共卫生问题，与孕产妇和胎儿的不良结局（如早产、低出生体重和死胎）有关。本系统综述和荟萃分析（SRMA）旨在综合怀孕期间自杀行为与胎母结局之间关联的证据，解决现有文献中的空白。材料和方法：SRMA遵循PRISMA 2020指南，纳入了报告有自杀行为（自杀意念、自杀计划或自杀企图）的孕妇的孕产妇和胎儿结局的观察性研究。截至2025年4月30日，检索了四个数据库（PubMed、Embase、Web of Science和Cochrane），纳入了18项研究。偏倚风险评估采用纽卡斯尔-渥太华量表。采用随机效应模型对数据进行分析，计算合并相对风险（rr）和95%置信区间（ci）。结果：从纳入SRMA的18项研究中，共分析了30749705名参与者，其中6557人属于自杀行为组。自杀行为显著增加了早产（RR = 1.78, 95% CI: 1.7-1.86）、早产（RR = 1.40, 95% CI: 1.26-1.55）、胎儿异常（RR = 1.84, 95% CI: 1.22-2.77）和低出生体重（RR = 1.83, 95% CI: 1.67-2.02）的风险，且无异质性（I²= 0%）。死产风险明显升高（RR = 11.92, 95% CI: 10.32 ~ 13.77）。其他结果，如胎盘早剥和产后出血，也显示出增加的风险。所有结果的证据确定性都很低或很低。结论：怀孕期间的自杀行为对孕产妇和胎儿健康构成重大风险，强调早期识别和干预的必要性。产前护理必须优先处理产妇心理健康问题，以改善母亲和儿童的结果。其他：协议已经注册到普洛斯彼罗（ID: CRD42024539860）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Women's Mental Health 医学-精神病学

CiteScore

8.00

自引率

4.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.