Selective electrochemical sensor for bisphenol A detection in wastewater using molecularly imprinted polymers on sustainable magnetic graphene oxide

IF 5.3 2区化学 Q1 CHEMISTRY, ANALYTICAL

Microchimica Acta Pub Date : 2025-10-10 DOI:10.1007/s00604-025-07577-0

Pablo Montoro-Leal, Maria del Mar Lopez Guerrero, Lourdes Mena-Herrera, Elisa Vereda Alonso, Antonio J. Ruiz-Sánchez, Rebeca Jiménez-Pérez

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Abstract

A modified screen-printed carbon electrode (SPCE) has been developed for the determination of bisphenol A (BPA), a compound widely used in plastics and resins production, which can disrupt endocrine and reproductive human systems. Magnetic graphene oxide (MGO) was synthesized following a sustainable protocol based on mechanochemistry. Then, MGO was combined with a molecularly imprinted pyrrole-based polymer (MIPPy) for the preparation of a novel magnetic nanocomposite (BPA@MIPPy), characterized by several imaging, spectroscopic, and electrochemical techniques. The magnetic properties of BPA@MIPPy allowed the manipulation of the material, including separation, analyte preconcentration, and electrode modification. Differential pulse voltammetry (DVP) was the selected electrochemical technique for BPA detection, presenting high sensitivity (LOD = 29 nM, LOQ = 97 nM) and precision under optimum conditions. To study selectivity, the response of the sensor toward four potential interferents was evaluated (phenol, methanol, sodium nitrate, and ascorbic acid), and no interference was observed. Finally, a real wastewater sample was successfully analyzed, demonstrating that the method is adequate for water-control applications.

Graphical Abstract

Abstract Image

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基于可持续磁性氧化石墨烯分子印迹聚合物的废水双酚A选择性电化学传感器

双酚A （BPA）是一种广泛应用于塑料和树脂生产的化合物，可干扰人体内分泌和生殖系统。磁性氧化石墨烯（MGO）是根据机械化学的可持续方案合成的。然后，将MGO与分子印迹吡咯基聚合物（MIPPy）结合，制备了一种新型磁性纳米复合材料（BPA@MIPPy），该复合材料通过多种成像、光谱和电化学技术进行了表征。BPA@MIPPy的磁性特性允许对材料进行操作，包括分离，分析物预富集和电极修饰。选择差分脉冲伏安法（DVP）作为双酚a检测的电化学技术，在最佳条件下具有较高的灵敏度（LOD = 29 nM, LOQ = 97 nM）和精密度。为了研究选择性，我们评估了传感器对四种潜在干扰物（苯酚、甲醇、硝酸钠和抗坏血酸）的响应，没有观察到干扰。最后，成功地分析了一个真实的废水样品，证明了该方法适用于水控制应用。图形抽象

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来源期刊

Microchimica Acta 化学-分析化学

CiteScore

9.80

自引率

5.30%

发文量

410

审稿时长

2.7 months

期刊介绍： As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.