Determinants of mortality risk in older adults from the ELSIA study: a prospective cohort study.

IF 1.6 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Sao Paulo Medical Journal Pub Date : 2025-10-06 eCollection Date: 2025-01-01 DOI:10.1590/1516-3180.2024.0402.R1.24032025
Lucas Lima Galvão, Douglas de Assis Teles Santos, Claudio Andre Barbosa de Lira, Jair Sindra Virtuoso Júnior, Sheilla Tribess, Ricardo Borges Viana, Anne Sulivan Lopes da Silva Reis, Katja Weiss, Beat Knechtle, Rodrigo Luiz Vancini
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引用次数: 0

Abstract

Background: This study investigated factors that may determine longevity in older adults, aiming to prolong their life expectancy and improve projections from before the coronavirus disease 2019 pandemic.

Objective: To identify risk factors for mortality in older Brazilian adults.

Design and setting: A prospective cohort study, part of the Estudo Longitudinal de Saúde do Idoso de Alcobaça.

Methods: This study included 332 older adults of both sexes who were followed up for over five years (2015-2020). Vital status was determined via telephone follow-up, information provided by family members, and death certificates. To identify the sociodemographic, health, functional, and behavioral factors associated with mortality risk among older adults, Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).

Results: The risk factors for mortality among older adults included the number of people living with them (HR = 1.22; 95%CI = 1.07-1.38) and the number of prescribed drugs (HR = 1.15; 95%CI = 1.00-1.32). Factors associated with a lower risk of mortality were greater time spent in physical activity (HR = 0.99; 95%CI = 0.90-0.99) and greater hip circumference (HR = 0.95; 95%CI = 0.31-0.99).

Conclusions: Sociodemographic, health, functional, and behavioral factors are determinants of mortality risk among older adults. Regular screening of the older adult population should be conducted to assess their general health status, allowing for more appropriate interventions to increase their quality of life and improve aging.

Abstract Image

ELSIA研究中老年人死亡风险的决定因素:一项前瞻性队列研究。
背景:本研究调查了可能决定老年人寿命的因素,旨在延长老年人的预期寿命,并改善2019年冠状病毒病大流行前的预测。目的:确定巴西老年人死亡的危险因素。设计和背景:一项前瞻性队列研究,是Saúde do Idoso de alcoba纵向研究的一部分。方法:本研究包括332名男女老年人,随访时间超过5年(2015-2020年)。通过电话随访、家庭成员提供的信息和死亡证明确定生命状况。为了确定与老年人死亡风险相关的社会人口学、健康、功能和行为因素,使用Cox比例风险回归来估计风险比(hr)和95%置信区间(ci)。结果:老年人死亡的危险因素包括同住人数(HR = 1.22, 95%CI = 1.07 ~ 1.38)和处方药物数量(HR = 1.15, 95%CI = 1.00 ~ 1.32)。与较低死亡风险相关的因素是体力活动时间较长(HR = 0.99; 95%CI = 0.90-0.99)和臀围较大(HR = 0.95; 95%CI = 0.31-0.99)。结论:社会人口、健康、功能和行为因素是老年人死亡风险的决定因素。应定期对老年人口进行筛查,以评估他们的一般健康状况,以便采取更适当的干预措施,提高他们的生活质量,改善老龄化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Sao Paulo Medical Journal
Sao Paulo Medical Journal 医学-医学:内科
CiteScore
2.20
自引率
7.10%
发文量
210
审稿时长
6-12 weeks
期刊介绍: Published bimonthly by the Associação Paulista de Medicina, the journal accepts articles in the fields of clinical health science (internal medicine, gynecology and obstetrics, mental health, surgery, pediatrics and public health). Articles will be accepted in the form of original articles (clinical trials, cohort, case-control, prevalence, incidence, accuracy and cost-effectiveness studies and systematic reviews with or without meta-analysis), narrative reviews of the literature, case reports, short communications and letters to the editor. Papers with a commercial objective will not be accepted.
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