Siyuan Yang, Xiaoyu Ji, Dejing Cheng, Chengyuan Ji
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引用次数: 0
Abstract
Background: This study aimed at delineating the temporal trends of epilepsy among women of childbearing age (WCBA), offering essential insights for prevention and management approaches in specific population.
Methods: Data from the Global Burden of Disease (GBD) 2021 were used to measure the burden of epilepsy among WCBA by region, country, age, and sociodemographic index (SDI). Age-period-cohort model, joinpoint regression analysis and the Auto Regressive Integrated Moving Average (ARIMA) model were carried out.
Results: The global prevalence, years-lived with disability (YLDs) rates of idiopathic epilepsy among WCBA show a decrease in 2021 compared with 1992, while the global prevalence and YLDs rates of secondary epilepsy increased; notably, the absolute number of cases has continued to rise. Low, low-middle and middle SDI regions face a growing epilepsy burden compared with higher SDI regions while high-SDI regions also showed higher idiopathic epilepsy prevalence among WCBA. The age effect revealed a general decline in idiopathic and total epilepsy prevalence with increasing age across global and SDI regions, in contrast to a progressive rise in secondary epilepsy prevalence. Unfavorable period effects of idiopathic and secondary epilepsy among WCBA were mostly exhibited in low, low-middle, middle and high SDI region. Favorable birth cohort effects were always seen in high-middle SDI region.
Conclusions: This study elucidates the complex epidemiological landscape of epilepsy among WCBA, noting a increase in disease burden. Strengthening epilepsy health education, optimizing WCBA epilepsy diagnosis and treatment and emphasizing WCBA epilepsy prevention can effectively reduce new cases of epilepsy and related disabilities.
期刊介绍：
Neurological Sciences is intended to provide a medium for the communication of results and ideas in the field of neuroscience. The journal welcomes contributions in both the basic and clinical aspects of the neurosciences. The official language of the journal is English. Reports are published in the form of original articles, short communications, editorials, reviews and letters to the editor. Original articles present the results of experimental or clinical studies in the neurosciences, while short communications are succinct reports permitting the rapid publication of novel results. Original contributions may be submitted for the special sections History of Neurology, Health Care and Neurological Digressions - a forum for cultural topics related to the neurosciences. The journal also publishes correspondence book reviews, meeting reports and announcements.
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