Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives.

IF 2.8 4区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

ChemPlusChem Pub Date : 2025-10-09 DOI:10.1002/cplu.202500314

Silvia Roscales, Aurelio G Csáky

引用次数: 0

Abstract

Nitrosoarenes exhibit a variety of biological and pharmacological activities. This review uncovers their utility as therapeutic agents, which extends to oxidative stress regulation, DNA damage and repair interaction, cyclin-dependent kinase inhibitors, anticancer, antiviral, antibacterial, antifungal, antiparasitic, anti-inflammatory, and other miscellaneous effects. The synthesis of the most relevant targets is also reviewed.

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亚硝基（杂）芳烃衍生物的药物发现与应用。

亚硝基芳烃具有多种生物学和药理活性。这篇综述揭示了它们作为治疗药物的用途，包括氧化应激调节、DNA损伤和修复相互作用、周期蛋白依赖性激酶抑制剂、抗癌、抗病毒、抗菌、抗真菌、抗寄生虫、抗炎和其他杂项作用。还审查了最相关指标的综合。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ChemPlusChem CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

5.90

自引率

0.00%

发文量

200

审稿时长

1 months

期刊介绍： ChemPlusChem is a peer-reviewed, general chemistry journal that brings readers the very best in multidisciplinary research centering on chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. Fully comprehensive in its scope, ChemPlusChem publishes articles covering new results from at least two different aspects (subfields) of chemistry or one of chemistry and one of another scientific discipline (one chemistry topic plus another one, hence the title ChemPlusChem). All suitable submissions undergo balanced peer review by experts in the field to ensure the highest quality, originality, relevance, significance, and validity.