Biophotonics technologies for skin disease diagnosis and monitoring

Abstract

Biophotonics technologies, such as photoacoustic imaging, two-photon microscopy, Raman spectroscopy, optical coherence tomography, diffuse reflectance spectroscopy and imaging, enable non-invasive clinical skin diagnostics by providing structural, functional and biochemical information. This Comment explores their clinical potential, highlighting key advances and challenges to overcome in translating them into routine dermatological diagnostic tools.