Synthesis and characterization of fuel-water interface-targeted antibacterial agents for fuel tanks

IF 13.2 1区工程技术 Q1 ENGINEERING, CHEMICAL

Chemical Engineering Journal Pub Date : 2025-10-09 DOI:10.1016/j.cej.2025.169425

Lijia Liu, Jing Wang, Ning Wu, Lihua Geng, Yang Yue, Xiaodong Zhao, Jingli Huang, Quanbin Zhang

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引用次数: 0

Abstract

Fuel system biodeterioration has persisted as an unresolved engineering challenge. The development of amphiphilic antibacterial agents holds immense significance for the inhibition of microbial activity and biofilm formation in oil-water interface in aircraft fuel tanks. In this study, we developed a hydroxypropyl trimethyl ammonium-O-alkyl chitosan (TTAC), an amphiphilic polymer with hydrophilic quaternary ammonium and hydrophobic alkyl chains, as a novel targeted (fuel-water interface-active) antimicrobial agent for aviation fuel system protection. Characterization was done using FT-IR and ¹H NMR spectroscopy. The water contact angle measurement yielded a result of θ = 75.84°. Antimicrobial performance showed potent activity with MICs of 8 mg/L (Acinetobacter lwoffii), 32 mg/L (Pseudomonas aeruginosa, Acinetobacter soli), 128 mg/L (Shewanella algae) and 64 mg/L (Escherichia coli, Staphylococcus aureus); MBCs were 16, 64, 256, and 128 mg/L respectively. Scanning electron microscopy (SEM) analysis of the fuel-water interface showed the densest biofilm at the interface, which was significantly reduced by TTAC treatment. TTAC treatment enhanced engineering stress by 11.9 % (Acinetobacter lwoffii) and 6.4 % (Pseudomonas aeruginosa) compared to untreated samples after microbial exposure. These results position TTAC as a promising multifunctional additive for next-generation fuel system preservation, offering simultaneous microbial control and metallic substrate protection. The amphiphilic action mechanism indicates specific utility in the complex fuel-water interface environments typical of modern aircraft fuel systems.

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燃料箱燃料-水界面靶向抗菌剂的合成与表征

燃料系统的生物降解一直是一个未解决的工程挑战。两亲性抗菌剂的开发对抑制飞机油箱油水界面微生物活性和生物膜的形成具有重要意义。在本研究中，我们开发了一种具有亲水性季铵盐和疏水性烷基链的两亲性聚合物羟丙基三甲基氨- o -烷基壳聚糖（TTAC），作为一种新型的靶向（燃料-水界面活性）航空燃油系统抗菌剂。采用FT-IR和1H NMR进行表征。水接触角测量结果为θ = 75.84°。抗菌性能显示，mic为8 mg/L （lwoffi不动杆菌）、32 mg/L（铜绿假单胞菌、soli不动杆菌）、128 mg/L（希瓦氏藻）和64 mg/L（大肠杆菌、金黄色葡萄球菌）；MBCs分别为16、64、256、128 mg/L。扫描电镜（SEM）分析表明，在燃料水界面处生物膜密度最大，经TTAC处理后生物膜密度明显降低。与未处理的微生物暴露后的样品相比，TTAC处理使工程应激增加了11.9 % （lwoffii不动杆菌）和6.4 %（铜绿假单胞菌）。这些结果将TTAC定位为下一代燃料系统保存的有前途的多功能添加剂，同时提供微生物控制和金属底物保护。两亲作用机理在现代飞机燃油系统的复杂燃油-水界面环境中具有特殊的应用价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemical Engineering Journal 工程技术-工程：化工

CiteScore

21.70

自引率

9.30%

发文量

6781

审稿时长

2.4 months

期刊介绍： The Chemical Engineering Journal is an international research journal that invites contributions of original and novel fundamental research. It aims to provide an international platform for presenting original fundamental research, interpretative reviews, and discussions on new developments in chemical engineering. The journal welcomes papers that describe novel theory and its practical application, as well as those that demonstrate the transfer of techniques from other disciplines. It also welcomes reports on carefully conducted experimental work that is soundly interpreted. The main focus of the journal is on original and rigorous research results that have broad significance. The Catalysis section within the Chemical Engineering Journal focuses specifically on Experimental and Theoretical studies in the fields of heterogeneous catalysis, molecular catalysis, and biocatalysis. These studies have industrial impact on various sectors such as chemicals, energy, materials, foods, healthcare, and environmental protection.