{"title":"A Quick Reference on Anion Gap and Strong Ion Gap.","authors":"Carlos Torrente Artero","doi":"10.1016/j.cvsm.2025.09.004","DOIUrl":null,"url":null,"abstract":"<p><p>Metabolic acid-base disorders frequently occur in emergency and critically ill patients. Recognizing these disturbances can be challenging, particularly when multiple acid-base imbalances coexist within a single patient. The anion gap (AG) and strong ion gap (SIG) are valuable calculations that help identify complex metabolic acid-base disturbances associated with unmeasured anions. This review provides definitions, reference values, indications, limitations, and guidelines for interpreting AG and SIG changes in clinical settings.</p>","PeriodicalId":49380,"journal":{"name":"Veterinary Clinics of North America-Small Animal Practice","volume":" ","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary Clinics of North America-Small Animal Practice","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1016/j.cvsm.2025.09.004","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Metabolic acid-base disorders frequently occur in emergency and critically ill patients. Recognizing these disturbances can be challenging, particularly when multiple acid-base imbalances coexist within a single patient. The anion gap (AG) and strong ion gap (SIG) are valuable calculations that help identify complex metabolic acid-base disturbances associated with unmeasured anions. This review provides definitions, reference values, indications, limitations, and guidelines for interpreting AG and SIG changes in clinical settings.
期刊介绍:
Veterinary Clinics of North America: Small Animal Practice offers you the most current information on the treatment of small animals such as cats and dogs, updates you on the latest advances, and provides a sound basis for choosing treatment options. Published bi-monthly—in January, March, May, July, September, November—each issue focuses on a single topic in small animal practice, including endocrinology, fluids and electrolytes, gastroenterology, infectious diseases, neurology, oncology, urology, respiratory issues , surgical information, small animal behavior, laboratory medicine, imaging methods, and nutrition.