Transient dilated cardiomyopathy phenotype and positive Bartonella serology in a cat.

IF 1.3 2区 农林科学 Q2 VETERINARY SCIENCES
B Ditzler, B Lozano, C Jones, M Henderson, A B Saunders
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引用次数: 0

Abstract

A one-and-a-half-year-old spayed female domestic shorthaired cat, originally obtained as a stray, presented with a two-day history of lethargy, anorexia, and progressive dyspnea. Point-of-care ultrasound showed marked bilateral pleural effusion and a small volume of ascites. Thoracocentesis resulted in the removal of 220 mL of protein poor transudate. Subsequently, a gallop was auscultated and an echocardiogram was performed. Significant findings on echocardiography were a dilated cardiomyopathy phenotype characterized by biventricular eccentric hypertrophy with normal left ventricular diastolic wall thickness and reduced biventricular systolic function with biatrial enlargement. The cat was fed a standard diet and had adequate plasma and whole blood taurine concentration. Infectious disease testing detected Bartonella spp. immunoglobulin G antibodies (1:512) including Bartonella vinsonii of which the cat is not a natural reservoir host. The cat was treated for dilated cardiomyopathy and congestive heart failure with pimobendan, furosemide, and clopidogrel as well as with pradofloxacin and doxycycline for suspected bartonellosis. At 2.5-, 5-, and 9-month rechecks, echocardiogram findings were markedly improved with a reduction in atrial and ventricular chamber enlargement to normal and normal ventricular systolic function and without any further evidence of congestive heart failure. Repeat Bartonella spp. titers were unchanged at 2.5 months. This case describes reverse remodeling of a dilated cardiomyopathy phenotype and resolution of congestive heart failure with discontinuation of cardiac medications in a young cat with suspected Bartonella myocarditis.

一只一岁半的雌性家养短毛猫,最初是作为流浪猫获得的,出现了两天的嗜睡,厌食和进行性呼吸困难的历史。即时超声显示双侧明显胸腔积液和少量腹水。经胸穿刺术取出220毫升蛋白质漏出物。随后,听诊疾驰并进行超声心动图检查。超声心动图的重要发现是扩张型心肌病,其特征是双室偏心肥厚,左室舒张壁厚度正常,双室收缩功能减弱,双房扩大。猫被喂食标准饮食,血浆和全血牛磺酸浓度充足。传染病检测检测到巴尔通体免疫球蛋白G抗体(1:12 12),包括猫不是其天然宿主的文氏巴尔通体。这只猫因扩张性心肌病和充血性心力衰竭接受了匹莫苯丹、呋塞米和氯吡格雷的治疗,并因疑似巴尔通体病接受了普拉多沙星和多西环素的治疗。在2.5个月、5个月和9个月复查时,超声心动图结果明显改善,心房和心室增大至正常和心室收缩功能正常,无进一步充血性心力衰竭的证据。重复巴尔通体滴度在2.5个月时保持不变。本病例描述了扩张型心肌病表型的反向重塑和充血性心力衰竭的解决与停止心脏药物在一个年轻的猫怀疑巴尔通体心肌炎。
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来源期刊
Journal of Veterinary Cardiology
Journal of Veterinary Cardiology VETERINARY SCIENCES-
CiteScore
2.50
自引率
25.00%
发文量
66
审稿时长
154 days
期刊介绍: The mission of the Journal of Veterinary Cardiology is to publish peer-reviewed reports of the highest quality that promote greater understanding of cardiovascular disease, and enhance the health and well being of animals and humans. The Journal of Veterinary Cardiology publishes original contributions involving research and clinical practice that include prospective and retrospective studies, clinical trials, epidemiology, observational studies, and advances in applied and basic research. The Journal invites submission of original manuscripts. Specific content areas of interest include heart failure, arrhythmias, congenital heart disease, cardiovascular medicine, surgery, hypertension, health outcomes research, diagnostic imaging, interventional techniques, genetics, molecular cardiology, and cardiovascular pathology, pharmacology, and toxicology.
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