Echocardiographic description of shunt volume in dogs with patent ductus arteriosus

IF 1.3 2区农林科学 Q2 VETERINARY SCIENCES

Journal of Veterinary Cardiology Pub Date : 2025-09-08 DOI:10.1016/j.jvc.2025.09.001

L.S. Köster , A.B. Asbury , C.M. Springer

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引用次数: 0

Abstract

Introduction/Objectives

Patent ductus arteriosus (PDA) can have a variable clinical course. The aims of this study were to describe Doppler estimates of shunt volume and their association with clinical and echocardiographic abnormalities.

Animals, Materials and Methods

Dogs with a diagnosis of a PDA on echocardiography were included in this study. Signalment, clinical signs, Doppler estimates of shunt volume, and outcome were collected from medical records (June 2020 and 2023) and examined for statistical associations. Groups included hemodynamically insignificant, incidental left-to-right (LR) shunt, left-to-right shunt with congestive heart failure (LCHF), and pulmonary hypertension (PH).

Results

Most dogs had standard LR shunts (76%), 4/4 heart murmur (69%), closing Doppler pattern characterized by—continuous LR shunting and high velocity (71%), and a color flow Doppler pattern—extending to the pulmonic valve (51%). Larger left ventricular chambers and normalized color flow Doppler width (CFDw) (P=0.023) were found in clinical as compared to asymptomatic dogs. Transmitral peak E (E), left ventricular outflow tract velocities, and color flow Doppler pixilation percent fill of the main pulmonary artery (CFD%) were correlated with left chamber dimensions. The LCHF group had a larger CFDw than the LR shunt group (P=0.009), which in turn was larger than that of the PH group (P=0.004). The mean CFD% was larger in the LCHF group (P=0.008) than in the LR-shunt group.

Study Limitations

The retrospective data collection limited standardization of image acquisition. Applicability is further limited by lack of intra-observer and interobserver variability analyses.

Conclusions

Doppler measures of shunt volume in dogs with PDA include E- and left ventricular outflow tract velocities, CFDw, and CFD%.

查看原文本刊更多论文

动脉导管未闭犬分流容积的超声心动图描述。

简介/目的：动脉导管未闭（PDA）有不同的临床病程。本研究的目的是描述多普勒估计分流容量及其与临床和超声心动图异常的关系。动物、材料和方法：本研究纳入超声心动图诊断为PDA的犬。从医疗记录（2020年6月和2023年6月）中收集信号、临床体征、分流体积的多普勒估计和结果，并检查统计关联。各组包括血流动力学不显著、偶发左向右分流、左向右分流合并充血性心力衰竭（LCHF）和肺动脉高压（PH）。结果：大多数狗有标准的左左分流（76%），4/4心脏杂音（69%），以连续左左分流和高流速为特征的闭合多普勒模式（71%），以及延伸到肺动脉瓣的彩色血流多普勒模式（51%）。与无症状犬相比，临床发现左心室增大，归一化彩色血流多普勒宽度（CFDw）（P=0.023）。透射峰E (E)、左室流出道速度、肺动脉彩色血流多普勒像素化填充率（CFD%）与左室尺寸相关。LCHF组CFDw大于LR分流术组（P=0.009），而LCHF组CFDw又大于PH组（P=0.004）。LCHF组的平均CFD%大于lr分流组（P=0.008）。研究局限性：回顾性数据收集限制了图像采集的标准化。由于缺乏观察者内部和观察者之间的可变性分析，适用性进一步受到限制。结论：PDA犬分流容量的多普勒测量包括左室和左室流出道速度、CFDw和CFD%。

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来源期刊

Journal of Veterinary Cardiology VETERINARY SCIENCES-

CiteScore

2.50

自引率

25.00%

发文量

审稿时长

154 days

期刊介绍： The mission of the Journal of Veterinary Cardiology is to publish peer-reviewed reports of the highest quality that promote greater understanding of cardiovascular disease, and enhance the health and well being of animals and humans. The Journal of Veterinary Cardiology publishes original contributions involving research and clinical practice that include prospective and retrospective studies, clinical trials, epidemiology, observational studies, and advances in applied and basic research. The Journal invites submission of original manuscripts. Specific content areas of interest include heart failure, arrhythmias, congenital heart disease, cardiovascular medicine, surgery, hypertension, health outcomes research, diagnostic imaging, interventional techniques, genetics, molecular cardiology, and cardiovascular pathology, pharmacology, and toxicology.