Rym Afiouni, Reine Merhy, Maria Farhat, Hampig Kourie, Roland Tomb
{"title":"Amyopathic Dermatomyositis in a Patient With Breast Cancer in Remission: A Case Report and a Systematic Review of the Literature.","authors":"Rym Afiouni, Reine Merhy, Maria Farhat, Hampig Kourie, Roland Tomb","doi":"10.1155/crdm/9193986","DOIUrl":null,"url":null,"abstract":"<p><p>Amyopathic dermatomyositis is a rare inflammatory disease in the spectrum of dermatomyositis characterized by typical skin lesions in the absence of muscle involvement. Dermatomyositis is a well-known paraneoplastic syndrome that can reveal or indicate a relapse of an underlying malignancy. To our knowledge, only a few cases of amyopathic dermatomyositis associated with breast cancer have been described in the literature. Here, we describe the case of a 52-year-old female with known triple-negative breast cancer in remission presenting with amyopathic dermatomyositis with a good response to hydroxychloroquine, and we performed a systematic review of this disease association. These patients should be followed closely for skin manifestations recurrence, therefore cancer recurrence or a new malignancy diagnosis.</p>","PeriodicalId":9630,"journal":{"name":"Case Reports in Dermatological Medicine","volume":"2025 ","pages":"9193986"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12497528/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Dermatological Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crdm/9193986","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Amyopathic dermatomyositis is a rare inflammatory disease in the spectrum of dermatomyositis characterized by typical skin lesions in the absence of muscle involvement. Dermatomyositis is a well-known paraneoplastic syndrome that can reveal or indicate a relapse of an underlying malignancy. To our knowledge, only a few cases of amyopathic dermatomyositis associated with breast cancer have been described in the literature. Here, we describe the case of a 52-year-old female with known triple-negative breast cancer in remission presenting with amyopathic dermatomyositis with a good response to hydroxychloroquine, and we performed a systematic review of this disease association. These patients should be followed closely for skin manifestations recurrence, therefore cancer recurrence or a new malignancy diagnosis.