Real-time estimation of boron concentration using an improved gamma-ray telescope system for boron neutron capture therapy.

IF 1.8 3区工程技术 Q3 CHEMISTRY, INORGANIC & NUCLEAR

Applied Radiation and Isotopes Pub Date : 2025-10-04 DOI:10.1016/j.apradiso.2025.112231

Yoshinori Sakurai, Da Fu, Takushi Takata, Hiroki Tanaka, Minoru Suzuki

引用次数: 0

Abstract

An online, real-time estimation method to determine the spatial distribution of boron-10 (B-10) concentrations is required for improved dose estimation in boron neutron capture therapy. By using a gamma-ray telescope technique to analyze the 478-keV prompt gamma rays generated from the nuclear reaction of B-10 with thermal neutrons, information regarding the B-10 concentration distribution can be obtained. The improved gamma-ray telescope system was settled at the Heavy Water Neutron Irradiation Facility of Kyoto University Reactor. Experimental verification of the improved telescope system was performed, and the experimental data were compared with the simulated data to calculate the specification coefficient that relates the design simulation to the actual measurement. From the experimental verification results, the effectiveness and usefulness of the improved gamma-ray telescope system were confirmed, and the specification coefficient was obtained.

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利用改进的伽玛射线望远镜系统进行硼中子俘获治疗的硼浓度实时估计。

为了改进硼中子俘获治疗的剂量估计，需要一种在线、实时的估算方法来确定硼-10 （B-10）浓度的空间分布。利用伽玛射线望远镜技术对B-10与热中子核反应产生的478 kev提示射线进行了分析，得到了B-10的浓度分布信息。改进后的伽玛射线望远镜系统安装在京都大学反应堆重水中子辐照装置上。对改进后的望远镜系统进行了实验验证，并将实验数据与仿真数据进行对比，计算出设计仿真与实际测量之间的规范系数。实验验证结果证实了改进后的伽玛望远镜系统的有效性和实用性，并得到了规范系数。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Radiation and Isotopes 工程技术-核科学技术

CiteScore

3.00

自引率

12.50%

发文量

406

审稿时长

13.5 months

期刊介绍： Applied Radiation and Isotopes provides a high quality medium for the publication of substantial, original and scientific and technological papers on the development and peaceful application of nuclear, radiation and radionuclide techniques in chemistry, physics, biochemistry, biology, medicine, security, engineering and in the earth, planetary and environmental sciences, all including dosimetry. Nuclear techniques are defined in the broadest sense and both experimental and theoretical papers are welcome. They include the development and use of α- and β-particles, X-rays and γ-rays, neutrons and other nuclear particles and radiations from all sources, including radionuclides, synchrotron sources, cyclotrons and reactors and from the natural environment. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. Papers dealing with radiation processing, i.e., where radiation is used to bring about a biological, chemical or physical change in a material, should be directed to our sister journal Radiation Physics and Chemistry.