Flexibly Reinforced Polycaprolactone Bioelectrodes for Piezoresistive Sensing via Direct Ink Writing.

IF 3.4 4区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of biomedical materials research. Part B, Applied biomaterials Pub Date : 2025-10-01 DOI:10.1002/jbm.b.35670

Yongpeng Wu, Jiabin Liu, Ronghan He, Xianwei Wang, Pan Xu, Nan Lin, Swee Hin Teoh, Chao Ma, Zuyong Wang

{"title":"Flexibly Reinforced Polycaprolactone Bioelectrodes for Piezoresistive Sensing via Direct Ink Writing.","authors":"Yongpeng Wu, Jiabin Liu, Ronghan He, Xianwei Wang, Pan Xu, Nan Lin, Swee Hin Teoh, Chao Ma, Zuyong Wang","doi":"10.1002/jbm.b.35670","DOIUrl":null,"url":null,"abstract":"Poly(ε-caprolactone) (PCL) is a biodegradable polyester known for its low melting point and high flexibility, making it ideal for various medical device applications. In this study, we introduce a conductive nanocarbon black-blended PCL as a reinforced ink for fabricating flexible and degradable piezoresistive bioelectrodes. This approach enables the creation of a piezoresistive bioelectrode optimized for precise biomechanical sensing. The bioelectrode exhibits exceptional mechanoelectrical stability under high tension (> 350%), repeated drawing (> 40%, 100 cycles), long-term bending (> 7000 cycles), extrusion (> 10,000 cycles), and torsion (> 90°). When assembled into flexible piezoresistive sensors, the sensor achieves a high sensitivity (2.66 kPa-1 in the range of 0-3 kPa), along with excellent repeatability and durability (10,000 cycles at 5 N). The sensor has promising applications in human health monitoring, including finger, wrist, and elbow activity tracking, as well as knee joint space sensing for guiding precise surgical operations.","PeriodicalId":15269,"journal":{"name":"Journal of biomedical materials research. Part B, Applied biomaterials","volume":"113 10","pages":"e35670"},"PeriodicalIF":3.4000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomedical materials research. Part B, Applied biomaterials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1002/jbm.b.35670","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}

引用次数: 0

Abstract

Poly(ε-caprolactone) (PCL) is a biodegradable polyester known for its low melting point and high flexibility, making it ideal for various medical device applications. In this study, we introduce a conductive nanocarbon black-blended PCL as a reinforced ink for fabricating flexible and degradable piezoresistive bioelectrodes. This approach enables the creation of a piezoresistive bioelectrode optimized for precise biomechanical sensing. The bioelectrode exhibits exceptional mechanoelectrical stability under high tension (> 350%), repeated drawing (> 40%, 100 cycles), long-term bending (> 7000 cycles), extrusion (> 10,000 cycles), and torsion (> 90°). When assembled into flexible piezoresistive sensors, the sensor achieves a high sensitivity (2.66 kPa^-1 in the range of 0-3 kPa), along with excellent repeatability and durability (10,000 cycles at 5 N). The sensor has promising applications in human health monitoring, including finger, wrist, and elbow activity tracking, as well as knee joint space sensing for guiding precise surgical operations.

查看原文本刊更多论文

柔性增强聚己内酯生物电极用于直接墨水书写压阻传感。

聚（ε-己内酯）（PCL）是一种可生物降解的聚酯，以其低熔点和高柔韧性而闻名，使其成为各种医疗器械应用的理想选择。在这项研究中，我们引入了一种导电的纳米炭黑混合PCL作为增强墨水，用于制造柔性和可降解的压阻性生物电极。这种方法可以创建一个压阻生物电极优化精确的生物力学传感。该生物电极在高压（>50%）、反复拉伸（> 40%，100次循环）、长期弯曲（> 7000次循环）、挤压（> 10000次循环）和扭转（> 90°）下表现出优异的力学稳定性。当组装成柔性压阻式传感器时，该传感器具有高灵敏度（在0-3 kPa范围内为2.66 kPa-1），以及出色的可重复性和耐用性（5 N下10,000次循环）。该传感器在人体健康监测方面有很好的应用前景，包括手指、手腕和肘部活动跟踪，以及膝关节空间感知，以指导精确的外科手术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of biomedical materials research. Part B, Applied biomaterials 工程技术-材料科学：生物材料

CiteScore

7.50

自引率

2.90%

发文量

199

审稿时长

12 months

期刊介绍： Journal of Biomedical Materials Research – Part B: Applied Biomaterials is a highly interdisciplinary peer-reviewed journal serving the needs of biomaterials professionals who design, develop, produce and apply biomaterials and medical devices. It has the common focus of biomaterials applied to the human body and covers all disciplines where medical devices are used. Papers are published on biomaterials related to medical device development and manufacture, degradation in the body, nano- and biomimetic- biomaterials interactions, mechanics of biomaterials, implant retrieval and analysis, tissue-biomaterial surface interactions, wound healing, infection, drug delivery, standards and regulation of devices, animal and pre-clinical studies of biomaterials and medical devices, and tissue-biopolymer-material combination products. Manuscripts are published in one of six formats: • original research reports • short research and development reports • scientific reviews • current concepts articles • special reports • editorials Journal of Biomedical Materials Research – Part B: Applied Biomaterials is an official journal of the Society for Biomaterials, Japanese Society for Biomaterials, the Australasian Society for Biomaterials, and the Korean Society for Biomaterials. Manuscripts from all countries are invited but must be in English. Authors are not required to be members of the affiliated Societies, but members of these societies are encouraged to submit their work to the journal for consideration.