Vitamin D status among pregnant women of North Macedonia: Assessing deficiency rates and associated risks factors.

IF 1.5 4区医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Medical Biochemistry Pub Date : 2025-09-05 DOI:10.5937/jomb0-55601

Boshku Aleksandra Atanasova, Vasko Aleksovski, Krstevska Slagana Simeonova, Nikolovska Elena Gjorgievska, Igor Samardjiski, Markova Ana Daneva

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引用次数: 0

Abstract

Background: Vitamin D is an essential vitamin that plays a key role in maintaining overall health. During pregnancy, the demand for vitamin D increases to support the growing needs of the fetus. Vitamin D deficiency is highly prevalent in pregnant women worldwide. Our study aimed to evaluate the vitamin D deficiency rate among pregnant women in the Republic of North Macedonia, along with influencing factors.

Methods: We conducted a prospective study of randomly selected pregnant women with different body mass indexes among vitamin supplementation users and non-users in two different seasons.

Results: A total of 309 pregnant women aged > 18 years were recruited from June 2022 to April 2023, with an average vitamin D concentration of 38.9 (36.6-40.2) nmol/L. During winter, 80.8 % of pregnant women had vitamin D deficiency.

Conclusions: Even though more than 77.3 % of pregnant women consume multivitamins containing vitamin D, vitamin D deficiency is highly prevalent among pregnant women, especially among obese pregnant women and during the winter months.

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北马其顿孕妇的维生素D状况：评估缺乏率和相关风险因素

背景：维生素D是一种必需的维生素，在维持整体健康方面起着关键作用。在怀孕期间，对维生素D的需求增加，以支持胎儿不断增长的需求。维生素D缺乏症在全世界的孕妇中非常普遍。本研究旨在评估北马其顿共和国孕妇维生素D缺乏率及其影响因素。方法：在两个不同季节随机选择不同体质指数的孕妇进行维生素补充者和未补充者的前瞻性研究。结果：从2022年6月至2023年4月共招募了309名年龄在bb0 - 18岁之间的孕妇，平均维生素D浓度为38.9 (36.6-40.2)nmol/L。在冬季，80.8%的孕妇缺乏维生素D。结论：尽管超过77.3%的孕妇服用含有维生素D的复合维生素，但维生素D缺乏症在孕妇中非常普遍，尤其是在肥胖孕妇和冬季。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Biochemistry BIOCHEMISTRY & MOLECULAR BIOLOGY-

CiteScore

3.00

自引率

12.00%

发文量

审稿时长

>12 weeks

期刊介绍： The JOURNAL OF MEDICAL BIOCHEMISTRY (J MED BIOCHEM) is the official journal of the Society of Medical Biochemists of Serbia with international peer-review. Papers are independently reviewed by at least two reviewers selected by the Editors as Blind Peer Reviews. The Journal of Medical Biochemistry is published quarterly. The Journal publishes original scientific and specialized articles on all aspects of clinical and medical biochemistry, molecular medicine, clinical hematology and coagulation, clinical immunology and autoimmunity, clinical microbiology, virology, clinical genomics and molecular biology, genetic epidemiology, drug measurement, evaluation of diagnostic markers, new reagents and laboratory equipment, reference materials and methods, reference values, laboratory organization, automation, quality control, clinical metrology, all related scientific disciplines where chemistry, biochemistry, molecular biology and immunochemistry deal with the study of normal and pathologic processes in human beings.