Subtotal vs gross total excision of vestibular schwannomas.

Q2 Medicine

Handbook of clinical neurology Pub Date : 2025-01-01 DOI:10.1016/B978-0-12-824534-7.00024-X

Ramin A Morshed, Tarun Arora, Philip V Theodospoulos

引用次数: 0

Abstract

Vestibular schwannomas are low-grade tumors of the eighth cranial nerve that lead to hearing loss, vestibular dysfunction, and eventual brainstem compression if significant growth occurs. Management of these tumors includes observation, radiosurgery, microsurgical resection, or a combination of these interventions. Although there has been a trend toward treatment with radiosurgery for smaller lesions, consensus reports still advocate for surgical resection in patients with large vestibular schwannomas. There has been a shift in management philosophy toward functional preservation rather than gross total resection, yet subtotal resection of vestibular schwannomas is associated with higher rates of recurrence on follow-up. In this chapter, we review common treatment modalities for VS and surgical indications. Additionally, we directly compare recurrence and complication rates after gross vs subtotal resection.

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前庭神经鞘瘤小全切除术与大体全切除术。

前庭神经鞘瘤是第八脑神经的低级别肿瘤，可导致听力丧失、前庭功能障碍，如果发生显著生长，最终导致脑干压迫。这些肿瘤的治疗包括观察、放射外科手术、显微外科手术切除或这些干预措施的结合。尽管对较小病变采用放射手术治疗已成为趋势，但共识报告仍然主张对较大的前庭神经鞘瘤患者进行手术切除。治疗理念已经转变为功能保留而不是全部切除，然而前庭神经鞘瘤的次全切除在随访中与较高的复发率相关。在本章中，我们回顾了常见的治疗方式VS和手术指征。此外，我们直接比较了大体切除与次全切除后的复发率和并发症发生率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Handbook of clinical neurology Medicine-Neurology (clinical)

CiteScore

4.10

自引率

0.00%

发文量

302

期刊介绍： The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published. In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d''être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension. Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols.