{"title":"Childhood Adversity and Cardiovascular Disease; Current Knowledge and Future Directions.","authors":"Shakira F Suglia","doi":"10.1007/s11886-025-02300-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>To review the current state of the science relating adverse childhood experiences (ACEs) and cardiovascular health and disease.</p><p><strong>Recent findings: </strong>Recent work has demonstrated associations between ACEs and development of cardiovascular disease (CVD) and has additionally shed a light on potential mechanistic pathways noting associations between ACEs and genomics, vascular health and cardiac structure. Existing work has advanced our understanding of the mechanisms by which ACEs are associated with CVD, yet much work remains particularly as we strive to understand how to ameliorate the impact of ACEs on CVD. Future research on interventions that promote cardiovascular health and integrate ACEs and emotional wellbeing are needed. A multilevel framework that understands how sociopolitical, neighborhood and family level factors contribute to childhood experiences is necessary to address the root causes of ACEs.</p>","PeriodicalId":10829,"journal":{"name":"Current Cardiology Reports","volume":"27 1","pages":"136"},"PeriodicalIF":3.3000,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Cardiology Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11886-025-02300-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: To review the current state of the science relating adverse childhood experiences (ACEs) and cardiovascular health and disease.
Recent findings: Recent work has demonstrated associations between ACEs and development of cardiovascular disease (CVD) and has additionally shed a light on potential mechanistic pathways noting associations between ACEs and genomics, vascular health and cardiac structure. Existing work has advanced our understanding of the mechanisms by which ACEs are associated with CVD, yet much work remains particularly as we strive to understand how to ameliorate the impact of ACEs on CVD. Future research on interventions that promote cardiovascular health and integrate ACEs and emotional wellbeing are needed. A multilevel framework that understands how sociopolitical, neighborhood and family level factors contribute to childhood experiences is necessary to address the root causes of ACEs.
期刊介绍：
The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature.
We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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