Abdul Moiz Khan, Syed Wajihullah Shah, Qazi Muhammad Safwan, Rida Akhtar, Jibran Ikram, Muhammad Abu Bakkar
{"title":"Unveiling Myoepithelioma: A Case Report and Literature Review of an Uncommon Soft Tissue Tumor.","authors":"Abdul Moiz Khan, Syed Wajihullah Shah, Qazi Muhammad Safwan, Rida Akhtar, Jibran Ikram, Muhammad Abu Bakkar","doi":"10.1002/ccr3.71177","DOIUrl":null,"url":null,"abstract":"<p><p>Myoepitheliomas are rare salivary gland tumors, comprising only 1%-1.5% of all cases. We report a unique case of a 69-year-old woman with a painless, slowly enlarging right parotid mass. CT imaging showed an ill-defined, irregular, multilobulated heterogeneous lesion compressing the deep parotid lobe. Fine-needle aspiration cytology suggested a benign spindle cell tumor. The patient underwent superficial parotidectomy, and histopathology confirmed a benign myoepithelioma with spindle and epithelioid cells, along with distinctive fibro-myxoid changes. Immunohistochemistry was positive for p63 and S-100. Postoperative recovery was uneventful, and no recurrence was noted at two-year follow-up. This case highlights the importance of considering myoepithelioma in elderly patients and demonstrates distinct radiological and histological features aiding diagnosis.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 10","pages":"e71177"},"PeriodicalIF":0.6000,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12496568/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/ccr3.71177","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Myoepitheliomas are rare salivary gland tumors, comprising only 1%-1.5% of all cases. We report a unique case of a 69-year-old woman with a painless, slowly enlarging right parotid mass. CT imaging showed an ill-defined, irregular, multilobulated heterogeneous lesion compressing the deep parotid lobe. Fine-needle aspiration cytology suggested a benign spindle cell tumor. The patient underwent superficial parotidectomy, and histopathology confirmed a benign myoepithelioma with spindle and epithelioid cells, along with distinctive fibro-myxoid changes. Immunohistochemistry was positive for p63 and S-100. Postoperative recovery was uneventful, and no recurrence was noted at two-year follow-up. This case highlights the importance of considering myoepithelioma in elderly patients and demonstrates distinct radiological and histological features aiding diagnosis.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).