{"title":"Management of vestibular schwannoma in the elderly.","authors":"Ahmed Helal, Mathew L Carlson, Michael J Link","doi":"10.1016/B978-0-12-824534-7.00025-1","DOIUrl":null,"url":null,"abstract":"<p><p>The elderly population has been expanding and is expected to continue to do so in the future. This, together with advances in work-up for SNHL, led to an increase in the incidence of VS, with smaller tumor sizes and older ages at the time of diagnosis. One-third of VS exhibit growth, with an average growth rate of 2mm/year. Larger extracanalicular tumors are more likely to grow independent of patient age. Patients with higher baseline SDS fare better, and those managed conservatively have a higher preservation of facial function. Despite extensive research, standardized treatment for VS has yet to be implemented, especially in the elderly population, given the many individual variations. Watchful waiting is a reasonable option for smaller tumors, especially on initial follow-up, providing the highest rates of hearing and facial nerve preservation. An alternative option, which is especially advantageous in high-risk elderly populations, is radiosurgery, providing more than 94% tumor control rate with roughly 57% hearing preservation rate on long-term follow-up. Radiosurgery may be used alone or as an adjunct to microsurgery. Finally, microsurgery remains a feasible option for properly selected elderly patients with reasonable surgical risk, and large Koos grade 4 tumors generally not amenable to radiosurgery.</p>","PeriodicalId":12907,"journal":{"name":"Handbook of clinical neurology","volume":"212 ","pages":"325-332"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Handbook of clinical neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/B978-0-12-824534-7.00025-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
The elderly population has been expanding and is expected to continue to do so in the future. This, together with advances in work-up for SNHL, led to an increase in the incidence of VS, with smaller tumor sizes and older ages at the time of diagnosis. One-third of VS exhibit growth, with an average growth rate of 2mm/year. Larger extracanalicular tumors are more likely to grow independent of patient age. Patients with higher baseline SDS fare better, and those managed conservatively have a higher preservation of facial function. Despite extensive research, standardized treatment for VS has yet to be implemented, especially in the elderly population, given the many individual variations. Watchful waiting is a reasonable option for smaller tumors, especially on initial follow-up, providing the highest rates of hearing and facial nerve preservation. An alternative option, which is especially advantageous in high-risk elderly populations, is radiosurgery, providing more than 94% tumor control rate with roughly 57% hearing preservation rate on long-term follow-up. Radiosurgery may be used alone or as an adjunct to microsurgery. Finally, microsurgery remains a feasible option for properly selected elderly patients with reasonable surgical risk, and large Koos grade 4 tumors generally not amenable to radiosurgery.
期刊介绍:
The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published. In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d''être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension. Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols.