Synthesis of 2,2′-Thiobis(N-arylacetamides) by Reaction of Primary Thioamides with N-Aryl-2-chloroacetamides

IF 0.8 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Russian Journal of General Chemistry Pub Date : 2025-10-07 DOI:10.1134/S1070363225603655

V. V. Dotsenko, A. Z. Temerdashev, N. A. Aksenov, I. V. Aksenova, B. S. Krivokolysko, S. G. Krivokolysko

引用次数: 0

Abstract

The reaction of thioacetamide, cyanothioacetamide, thiourea, 3-aryl-2-cyanothioacrylamides, (cyclohexylidene)cyanothioacetamide, or thiosemicarbazide with N-aryl-2-chloroacetamides in the presence of KOH in ethanol proceeds with the formation of the same products―2,2′-thiobis(N-arylacetamides)―in 62–93% yields. Structure of the products was confirmed by IR, NMR spectroscopy, and high-resolution mass spectrometry (HRMS).

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伯硫酰胺与n -芳基-2-氯乙酰酰胺反应合成2,2′-硫比斯(n -芳基乙酰酰胺

硫代乙酰胺、氰硫代乙酰胺、硫脲、3-芳基-2-氰硫代丙烯酰胺、（环己基）氰硫代乙酰胺或硫代氨基脲与n -芳基-2-氯乙酰胺在乙醇中以KOH存在的条件下反应，生成相同的产物- 2,2′-硫代（n -芳基乙酰胺），产率为62-93%。通过红外光谱、核磁共振光谱和高分辨率质谱（HRMS）对产物的结构进行了确证。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Russian Journal of General Chemistry 化学-化学综合

CiteScore

1.40

自引率

22.20%

发文量

252

审稿时长

2-4 weeks

期刊介绍： Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.