One-step construction of reduced graphene/silver nanogel interpenetrating cotton fabric antimicrobial dressing and its performance

IF 4 3区化学 Q2 POLYMER SCIENCE

Polymer Bulletin Pub Date : 2025-06-25 DOI:10.1007/s00289-025-05876-3

Baoxia Xue, Jiaxin Feng, Chunyan Zhang, Zhao An, Ziyang Shao, Jing Liu, Mei Niu, Li Zhang

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Abstract

As one of the most common medical dressings, imparting effective antibacterial properties to cotton (COT) fabric is a crucial strategy for preventing bacterial infections. To achieve the continuous release of silver ions, a novel one-step hydrothermal approach was developed by integrating reduced graphene oxide (rGO) and silver nanoparticles (AgNPs) into the fabric, resulting in the in situ growth of rGO/Ag aerogel on the surface of the cotton fabric (rGO/Ag/COT), and forming a new type of structured medical antibacterial dressing. Various analytical methods (including SEM, XRD, plate counting method, flow cytometry, and cytotoxicity) were employed to investigate the structure and properties of the rGO/Ag/COT dressing. The results indicated that, the rGO/Ag aerogel has been embedded within COT fabric via ester-based bonding. The rGO/Ag/COT dressing demonstrated a remarkable antimicrobial efficacy of 99.9% against Escherichia coli and Staphylococcus aureus, owned the ability to continuously release silver ions over a period of several days, and generated a significant amount of reactive oxygen species within the bacterial cells. Additionally, the rGO/Ag/COT dressing displayed the in vitro cytotoxicity of grade 1 and excellent biocompatibility. These implied this strategy provides more ideas for the field of medical dressings through the combination of aerogels and textiles.

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还原石墨烯/银纳米凝胶互穿棉织物抗菌敷料一步法制备及性能研究

棉织物作为最常用的医用敷料之一，赋予其有效的抗菌性能是防止细菌感染的关键策略。为了实现银离子的连续释放，开发了一种新的一步水热方法，将还原氧化石墨烯（rGO）和纳米银颗粒（AgNPs）整合到织物中，使rGO/Ag气凝胶在棉织物表面原位生长（rGO/Ag/COT），形成一种新型的结构化医用抗菌敷料。采用SEM、XRD、平板计数法、流式细胞术、细胞毒性等多种分析方法对rGO/Ag/COT填料的结构和性能进行了研究。结果表明，还原氧化石墨烯/银气凝胶通过酯基键合嵌入COT织物中。rGO/Ag/COT敷料对大肠杆菌和金黄色葡萄球菌的抗菌效果达到99.9%，具有在数天内持续释放银离子的能力，并在细菌细胞内产生大量活性氧。此外，rGO/Ag/COT敷料显示出1级的体外细胞毒性和良好的生物相容性。这意味着该策略通过气凝胶与纺织品的结合为医用敷料领域提供了更多的思路。

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来源期刊

Polymer Bulletin 化学-高分子科学

CiteScore

6.00

自引率

6.20%

发文量

审稿时长

5.5 months

期刊介绍： "Polymer Bulletin" is a comprehensive academic journal on polymer science founded in 1988. It was founded under the initiative of the late Mr. Wang Baoren, a famous Chinese chemist and educator. This journal is co-sponsored by the Chinese Chemical Society, the Institute of Chemistry, and the Chinese Academy of Sciences and is supervised by the China Association for Science and Technology. It is a core journal and is publicly distributed at home and abroad. "Polymer Bulletin" is a monthly magazine with multiple columns, including a project application guide, outlook, review, research papers, highlight reviews, polymer education and teaching, information sharing, interviews, polymer science popularization, etc. The journal is included in the CSCD Chinese Science Citation Database. It serves as the source journal for Chinese scientific and technological paper statistics and the source journal of Peking University's "Overview of Chinese Core Journals."