Recognizing non-neoplastic mimics of myeloid malignancies in the bone marrow and peripheral blood: pearls and pitfalls

Margaret Moore, Elizabeth L Courville
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引用次数: 0

Abstract

In this review, we outline benign conditions of bone marrow and blood that can mimic myeloid neoplasms. We discuss diagnostic pearls that we utilize in our daily clinical practice to avoid overdiagnosis or premature diagnosis of malignancy. Furthermore, we highlight pre-malignant conditions that pose diagnostic difficulties due to their overlapping features with myeloid neoplasms. Integration of bone marrow and peripheral blood findings with clinical and laboratory data is essential for accurate diagnosis, and we advocate for a stepwise approach with an internal “diagnostic checklist” to avoid misclassification.
识别骨髓和外周血中髓系恶性肿瘤的非肿瘤性模拟物:珍珠和陷阱
在这篇综述中,我们概述了骨髓和血液的良性状况,可以模拟髓系肿瘤。我们讨论诊断珍珠,我们利用在我们的日常临床实践,以避免过度诊断或过早诊断恶性肿瘤。此外,我们强调由于与髓系肿瘤的重叠特征而造成诊断困难的恶性前病变。将骨髓和外周血结果与临床和实验室数据相结合对于准确诊断至关重要,我们提倡采用内部“诊断清单”的逐步方法,以避免错误分类。
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来源期刊
Diagnostic Histopathology
Diagnostic Histopathology Medicine-Pathology and Forensic Medicine
CiteScore
1.30
自引率
0.00%
发文量
64
期刊介绍: This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.
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