Three‐Component Modular Synthesis of Maleimide‐Fused Carbazoles and Maleimide‐Fused Indoles Under Transition‐Metal‐Free Conditions

IF 4 2区化学 Q2 CHEMISTRY, APPLIED

Advanced Synthesis & Catalysis Pub Date : 2025-10-07 DOI:10.1002/adsc.70076

Qi Yin, Xinlin Zhou, Bin Tan, Xueao Wang, Jiao Liu, Guo‐Jun Deng, Shanping Chen

引用次数: 0

Abstract

An NH4I‐promoted three‐component cascade cyclization reaction for the modular synthesis of maleimide‐fused benzocarbazoles and maleimide‐fused indoles has been developed. The present approach starts from readily available indoles/pyrroles, cyclohexanones, and maleimides, affording variety of maleimide‐fused benzocarbazoles and maleimide‐fused indoles in 40–83% yields under metal‐free conditions.

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无过渡金属条件下马来酰亚胺-熔融咔唑和马来酰亚胺-熔融吲哚的三组分模块化合成

建立了一种NH4I促进的三组分级联环化反应，用于模块化合成马来酰亚胺熔融苯并咔唑和马来酰亚胺熔融吲哚。目前的方法从容易获得的吲哚/吡咯、环己酮和马来酰亚胺开始，在无金属条件下，以40-83%的产率提供各种马来酰亚胺熔融苯并咔唑和马来酰亚胺熔融吲哚。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advanced Synthesis & Catalysis 化学-应用化学

CiteScore

9.40

自引率

7.40%

发文量

447

审稿时长

1.8 months

期刊介绍： Advanced Synthesis & Catalysis (ASC) is the leading primary journal in organic, organometallic, and applied chemistry. The high impact of ASC can be attributed to the unique focus of the journal, which publishes exciting new results from academic and industrial labs on efficient, practical, and environmentally friendly organic synthesis. While homogeneous, heterogeneous, organic, and enzyme catalysis are key technologies to achieve green synthesis, significant contributions to the same goal by synthesis design, reaction techniques, flow chemistry, and continuous processing, multiphase catalysis, green solvents, catalyst immobilization, and recycling, separation science, and process development are also featured in ASC. The Aims and Scope can be found in the Notice to Authors or on the first page of the table of contents in every issue.