Human Papillomavirus Prevalence and Genotype Distribution in Dongguan, China.

IF 1.1 Q4 INFECTIOUS DISEASES

Journal of Global Infectious Diseases Pub Date : 2025-09-22 eCollection Date: 2025-07-01 DOI:10.4103/jgid.jgid_3_25

Minla Rao, Jianjun Chen, Wenbin Lai, Daogui Yang, Lisheng Wang, Hao Ouyang, Zhenggang Yin, Zhihuang Wu, Yanqing Chen, Qingru Zheng, Shayan Chen

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引用次数: 0

Abstract

Introduction: Cervical cancer is strongly associated with human papillomavirus (HPV) infection. In this retrospective study, we analyzed the data of individuals who were tested for HPV at Binhaiwan Central Hospital in Dongguan.

Methods: We retrospectively analyzed the data of 73,149 participants who underwent HPV examination at Binhaiwan Central Hospital in Dongguan. All participants were tested for HPV genotypes. We subsequently analyzed the infection rate and evaluated the distribution of HPV using the Chi-square test.

Results: The results suggest that the five most common HPV infection genotypes for men in the Dongguan area are different from those for women. The five most common high-risk HPV infections in women were the HPV52, 16, 58, 53, and 68 genotypes, whereas the five most common genotypes in men were HPV52, 16, 51, 58, and 39. The highest HPV infection positivity rate for female patients (31.68%) was in the 31-40 year age group, whereas the highest HPV infection positivity rate for male patients (40.47%) was in the 21-30 year age group.

Conclusions: These findings provide a theoretical basis for epidemiological investigations, clinical prevention, and treatment of HPV infection and HPV vaccination in the region. The results could provide valuable information for healthcare professionals and policymakers to develop targeted prevention and screening strategies for reducing the burden of HPV-related diseases in this population.

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东莞地区人乳头瘤病毒流行及基因型分布

宫颈癌与人乳头瘤病毒（HPV）感染密切相关。在这项回顾性研究中，我们分析了在东莞滨海湾中心医院接受HPV检测的个体数据。方法：回顾性分析在东莞市滨海湾中心医院接受HPV检查的73149例患者的资料。所有参与者都进行了HPV基因型检测。我们随后分析了感染率，并使用卡方检验评估了HPV的分布。结果：东莞地区男性最常见的5种HPV感染基因型与女性不同。女性中最常见的五种高危HPV感染是HPV52、16、58、53和68基因型，而男性中最常见的五种基因型是HPV52、16、51、58和39。女性患者HPV感染阳性率最高的年龄段为31-40岁（31.68%），男性患者HPV感染阳性率最高的年龄段为21-30岁（40.47%）。结论：本研究结果为该地区HPV感染的流行病学调查、临床预防和治疗及HPV疫苗接种提供了理论依据。该结果可为卫生保健专业人员和政策制定者制定有针对性的预防和筛查策略提供有价值的信息，以减轻该人群中hpv相关疾病的负担。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Global Infectious Diseases INFECTIOUS DISEASES-

CiteScore

3.30

自引率

0.00%

发文量

审稿时长

29 weeks

期刊介绍： JGID encourages research, education and dissemination of knowledge in the field of Infectious Diseases across the world thus promoting translational research by striking a synergy between basic science, clinical medicine and public health. The Journal intends to bring together scientists and academicians in Infectious Diseases to promote translational synergy between Laboratory Science, Clinical Medicine and Public Health. The Journal invites Original Articles, Clinical Investigations, Epidemiological Analysis, Data Protocols, Case Reports, Clinical Photographs, review articles and special commentaries. Students, Residents, Academicians, Public Health experts and scientists are all encouraged to be a part of this initiative by contributing, reviewing and promoting scientific works and science.