Ciyi Guan, Lei Wang, Chao Wang, Yinhua Ma, Yinjiao Chen, Junjun Wu, Hui Pan, Chang Zhang, Haiyuan Song
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引用次数: 0
Abstract
Objectives: To investigate the independent and combined associations of sleep duration and sleep disorders with the risk of overactive bladder (OAB) and identify threshold effects of sleep duration on OAB.
Methods: Data from the NHANES (2005-2018) were analyzed, including 27,302 adults, among whom 5,601 (20.5%) were diagnosed with OAB. Associations between sleep duration (≤ 6 h, > 6 to < 9 h, ≥ 9 h), sleep disorders, and OAB risk were assessed using multivariable logistic regression, restricted cubic splines (RCS), and smooth curve fitting, adjusting for demographic, socioeconomic, lifestyle, and health-related covariates.
Results: A significant non-linear, U-shaped relationship between sleep duration and OAB risk was observed. Compared to individuals with a sleep duration of 6-9 h, those with short sleep duration (≤ 6 h) had a slightly lower risk of OAB (OR = 0.94), while those with long sleep duration (≥ 9 h) had a significantly higher risk (OR = 2.54). Self-reported sleep disorders independently elevated the risk of OAB (OR = 1.46). RCS analysis identified 6 h of sleep as a critical inflection point.
Conclusion: This study reveals a U-shaped relationship between sleep duration and the risk of overactive bladder (OAB), with both short (≤ 6 h) and long (≥ 9 h) sleep durations increasing OAB risk. These findings highlight the importance of sleep management in OAB care. Behavioral interventions, including sleep hygiene education and bladder training, may help mitigate symptoms and improve patient outcomes.
期刊介绍：
Frontiers in Medicine publishes rigorously peer-reviewed research linking basic research to clinical practice and patient care, as well as translating scientific advances into new therapies and diagnostic tools. Led by an outstanding Editorial Board of international experts, this multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
In addition to papers that provide a link between basic research and clinical practice, a particular emphasis is given to studies that are directly relevant to patient care. In this spirit, the journal publishes the latest research results and medical knowledge that facilitate the translation of scientific advances into new therapies or diagnostic tools. The full listing of the Specialty Sections represented by Frontiers in Medicine is as listed below. As well as the established medical disciplines, Frontiers in Medicine is launching new sections that together will facilitate
- the use of patient-reported outcomes under real world conditions
- the exploitation of big data and the use of novel information and communication tools in the assessment of new medicines
- the scientific bases for guidelines and decisions from regulatory authorities
- access to medicinal products and medical devices worldwide
- addressing the grand health challenges around the world
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