Sustainable Uric Acid Detection Using Green-Synthesized MoO3 Thin Films

IF 2.5 4区工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC

Journal of Electronic Materials Pub Date : 2025-09-09 DOI:10.1007/s11664-025-12350-3

Bilasini Devi Naorem, Lipi Singh, Purohit Chirag, Sreejan Rayhan, Tejaswita, Jatinder Pal Singh, Babita Sharma, Arijit Chowdhuri, Monika Tomar, Mallika Verma, Neha Batra

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引用次数: 0

Abstract

Sustainable and eco-friendly biosensing technologies are emerging as a potential approach for healthcare improvement while simultaneously reducing environmental impact. In this study, a novel uric acid biosensor has been developed using green-synthesized molybdenum oxide (MoO₃) thin films, which demonstrates a creative way to repurpose waste for advanced technological applications. The structural and morphological studies confirmed the uniformity and high quality of the MoO₃ thin films, which played a key role in enhancing sensor performance. The fabricated biosensor demonstrated high sensitivity [244.76 µA/(mM cm²)], a fast response time of 5 s, and excellent selectivity against common interferents which are typically found in blood plasma. Additionally, the low Michaelis–Menten constant (Kₘ = 0.07311 mM) indicates that the enzyme maintained a strong affinity for uric acid, ensuring reliable detection even at low concentrations. In addition to its strong analytical performance, this work highlights the potential of green synthesis in the development of biosensors. By integrating eco-conscious material synthesis with high-performance sensing capabilities, this work lays the foundation for more sustainable, cost-effective, and efficient biosensors for healthcare applications. This approach not only enhances biosensing technology but also aligns with global efforts to minimize waste and promote greener alternatives in scientific innovation.

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绿色合成MoO3薄膜可持续尿酸检测

可持续和生态友好的生物传感技术正在成为改善医疗保健同时减少对环境影响的潜在方法。在这项研究中，利用绿色合成的氧化钼（MoO3）薄膜开发了一种新的尿酸生物传感器，这展示了一种将废物重新利用于先进技术应用的创新方法。结构和形态研究证实了MoO3薄膜的均匀性和高质量，这对提高传感器性能起着关键作用。该生物传感器具有高灵敏度[244.76µA/(mM cm2)]，快速响应时间为5 s，对血浆中常见的干扰具有良好的选择性。此外，低Michaelis-Menten常数（K ω = 0.07311 mM）表明该酶对尿酸保持了很强的亲和力，即使在低浓度下也能保证可靠的检测。除了其强大的分析性能外，这项工作还突出了绿色合成在生物传感器开发中的潜力。通过将具有生态意识的材料合成与高性能传感能力相结合，这项工作为医疗保健应用中更具可持续性、成本效益和效率的生物传感器奠定了基础。这种方法不仅提高了生物传感技术，而且与全球在科学创新中减少浪费和促进更环保替代品的努力保持一致。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Electronic Materials 工程技术-材料科学：综合

CiteScore

4.10

自引率

4.80%

发文量

693

审稿时长

3.8 months

期刊介绍： The Journal of Electronic Materials (JEM) reports monthly on the science and technology of electronic materials, while examining new applications for semiconductors, magnetic alloys, dielectrics, nanoscale materials, and photonic materials. The journal welcomes articles on methods for preparing and evaluating the chemical, physical, electronic, and optical properties of these materials. Specific areas of interest are materials for state-of-the-art transistors, nanotechnology, electronic packaging, detectors, emitters, metallization, superconductivity, and energy applications. Review papers on current topics enable individuals in the field of electronics to keep abreast of activities in areas peripheral to their own. JEM also selects papers from conferences such as the Electronic Materials Conference, the U.S. Workshop on the Physics and Chemistry of II-VI Materials, and the International Conference on Thermoelectrics. It benefits both specialists and non-specialists in the electronic materials field. A journal of The Minerals, Metals & Materials Society.