Small but mighty: emerging roles of uORFs in plants.

IF 14.9 1区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Trends in biotechnology Pub Date : 2025-10-03 DOI:10.1016/j.tibtech.2025.09.009

Farhad Nazarian-Firouzabadi, Jianing Bai, Cesar de la Fuente-Nunez

引用次数: 0

Abstract

The discovery and manipulation of upstream open reading frames (uORFs) represent a promising frontier in plant biotechnology, offering strategies to enhance disease resistance and crop resilience. Here, we explore the role of uORFs in regulating gene expression under biotic stress and discuss approaches to engineer uORFs for sustainable agriculture and precision breeding.

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小而强大：uorf在植物中的新兴作用。

上游开放阅读框架（uorf）的发现和操作代表了植物生物技术的一个有前景的前沿，为提高作物抗病性和抗逆性提供了策略。在此，我们探讨了uORFs在生物胁迫下调控基因表达的作用，并讨论了uORFs工程用于可持续农业和精准育种的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in biotechnology 工程技术-生物工程与应用微生物

CiteScore

28.60

自引率

1.20%

发文量

198

审稿时长

1 months

期刊介绍： Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems. The major themes that TIBTECH is interested in include: Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering) Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology) Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics) Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery) Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).