CCM-ITALUNG2 pilot on lung cancer screening in Italy: recruitment, integration with smoking cessation and baseline results.

IF 4.8 1区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiologia Medica Pub Date : 2025-10-04 DOI:10.1007/s11547-025-02109-5

Giuseppe Gorini, Donella Puliti, Giulia Picozzi, Jasmine Giovannoli, Giulia Veronesi, Francesco Pistelli, Carlo Senore, Carlo Tessa, Edoardo Cavigli, Simonetta Bisanzi, Elisa Dieci, Piergiorgio Muriana, Annalisa Deliperi, Emanuela Romano, Cristiano Piccinelli, Paola Vivani, Eugenio Paci, Laura Carrozzi, Mario Mascalchi, Enrica Stancanelli, Marika Furuya, Guglielmo Bonaccorsi, Giuseppe Cavallo, Giulia Carreras, Cristina Sani, Jessica Viti, Carmen Visioli, Giovanna Masala, Paola Mantellini, Diletta Cozzi, Katia Ferrari, Amedeo Vannacci, Serena Checcacci, Olga Smorchkova, Luca Gozzi, Alessandra Bindi, Chiara Moroni, Silvia Luvarà, Maurizio Bartolucci, Ilaria Orlandi, Chiara Cruschelli, Chiara Romei, Zeno Falaschi, Valentina Bessi, Stefano Paoli, Elisabetta Casto, Giulia Marchi, Giacomo Guglielmi, Beatrice Vivaldi, Natascia Coltelli, Guido Marchi, Lucia Lupetti, Michela Zanetti, Ilaria Stellati, Maila Coltelli, Simona De Santis, Stefano Viscardi, Domenico Ghio, Paolo Fonio, Riccardo Faletti, Andrea Di Chio, Tiziana Vavalà, Roberto Albera, Silvia Novello, Paola Gollini, Sandra Anglesio, Fabio Beatrice, Pavilio Piccioni, Cristina Fanini, Guido Guidoni, Valentina Galli, Patrizia Gai, Antonella Manfredi, Anna Di Natale, Marzio Taddei, Laura Fallani, Michela Fioriti, Michele Di Francesco, Alessandro Guerrini, Niccolò Biancalani, Barbara Calistri, Lara Romagnani, Luca Puccetti, Gianluca Sassi, Marco Araldi, Pier Riccardo Rossi, Sabina Bianchi, Annalisa Cannatelli, Paolo Cataldi, Roberto Cernigliaro, Francesca D'Agostino, Cristina De Ambrogio, Francesca Di Valente, Giulia Durando, Alessandra Fracchia, Eleonora Giraudi, Patrizia Guerra, Massimo Massi, Laura Mondino, Cristina Nolli, Chiara Pugni, Enrica Zucchetti, Stefano Diciotti

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引用次数: 0

Abstract

Background: The CCM-ITALUNG2 pilot was implemented to evaluate the feasibility of an organized lung cancer (LC) screening programme in five Italian centres.

Methods: The screening pathway included invitation, recruitment, referral to Smoking Cessation Services (SCSs), and use of the Lung-RADS score for low-dose CT reading. Dedicated screening operators followed up participants from recruitment through the clinical follow-up established by multidisciplinary teams. Eligibility criteria included age 55-75 years, ever-smokers with ≥ 25 pack-years; quit within the past 10 years. Baseline round results are presented.

Results: From November 2022 to May 2024, 1,144 of the 1,971 invited individuals (58.0%) were recruited following different strategies including in-person invitation by general practitioners (GPs; 356 subjects, 31.9%) or other healthcare personnel (18.1%), self-presentation (36.3%), and phone invitation using GPs' patient lists (13.7%). Among current smokers, 38.5% accepted referral to SCSs. Eighteen subjects (77.8% in stage I-II) were diagnosed with LC (prevalent LC rate 1.57%). The mean time to surgery was 147 days (standard deviation 73); the false-positive rate was 1.38% (15/1,085).

Conclusions: By utilizing different organizational models, the pilot was tailored to the specific characteristics of each centre. Phone invitations from GPs' patient lists, in-person invitations by GPs and other healthcare personnel, and self-presentation might enhance equity of access in comparison with self-referral only. Dedicated screening operators, the use of the Lung-RADS scoring system, and a structured clinical follow-up supported participants throughout the screening pathway. Delivering brief advice for smoking cessation during recruitment and offering SCS referral were feasible within the screening pathway.

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意大利肺癌筛查CCM-ITALUNG2试点：招募、戒烟整合和基线结果

背景：CCM-ITALUNG2试点项目在意大利的五个中心实施，以评估有组织的肺癌（LC）筛查项目的可行性。方法：筛查途径包括邀请、招募、转介到戒烟服务（scs），并使用肺- rads评分进行低剂量CT读数。专门的筛查操作员从招募参与者到多学科团队建立的临床随访进行随访。入选标准包括年龄55-75岁，既往吸烟者≥25包年；在过去10年内戒烟。给出了基准轮结果。结果：从2022年11月至2024年5月，1971名被邀请者中有1144人（58.0%）通过不同的策略被招募，包括全科医生（gp）亲自邀请（356名受试者，31.9%）或其他卫生保健人员（18.1%）、自我介绍（36.3%）和利用gp患者名单电话邀请（13.7%）。在目前吸烟者中，38.5%接受转诊到社会服务中心。18例（77.8%为I-II期）被诊断为LC （LC患病率1.57%）。平均手术时间147天（标准差73）；假阳性率为1.38%（15/ 1085）。结论：通过使用不同的组织模式，该试点适合每个中心的具体特点。全科医生病人名单的电话邀请，全科医生和其他医护人员的亲自邀请，以及自我介绍与自我转诊相比，可能会提高获得机会的公平性。专门的筛查操作者，肺- rads评分系统的使用，以及结构化的临床随访支持了整个筛查途径的参与者。在招募期间提供简短的戒烟建议和提供SCS转介在筛查途径内是可行的。

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来源期刊

Radiologia Medica 医学-核医学

CiteScore

14.10

自引率

7.90%

发文量

133

审稿时长

4-8 weeks

期刊介绍： Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.