Disaccharidase Deficiency in a Pediatric Patient With Autism Spectrum Disorder: Case Report.

IF 1.8 4区 医学 Q2 HEALTH POLICY & SERVICES
Micayla Meyers Madell, Marcy Weidkamp, Laurie Newton
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引用次数: 0

Abstract

This case report describes a 13-year-old patient diagnosed with autism spectrum disorder (ASD) and nonverbal communication who received an extensive workup for gastrointestinal (GI) concerns. The clinical presentation, diagnostic reasoning, therapeutic intervention, and follow-up are discussed. The frequency of GI tract symptoms in children with ASD ranges from 9% to 84%, compared with 9%-37% for children without ASD. Meta-analysis reveals that children with ASD experience significantly more general GI symptoms as well as higher rates of diarrhea, constipation, and abdominal pain. In this scenario, lactase deficiency was felt to be a contributing cause of acute changes in behavior and toileting habits. It can be difficult to assess pain in patients with ASD, and therefore, providers may be inclined to attribute new behaviors to the patient's developmental differences. This case highlights the importance of investigating multiple casualties of pain in children with ASD who are non-verbal or developmentally delayed.

儿童自闭症谱系障碍患者双糖酶缺乏:病例报告。
这个病例报告描述了一个13岁的被诊断为自闭症谱系障碍(ASD)和非语言交流的病人,他接受了胃肠(GI)问题的广泛检查。临床表现,诊断推理,治疗干预和随访进行了讨论。患有ASD的儿童出现胃肠道症状的频率从9%到84%不等,而没有ASD的儿童出现胃肠道症状的频率为9%到37%。荟萃分析显示,患有ASD的儿童明显有更多的一般胃肠道症状,以及更高的腹泻、便秘和腹痛发生率。在这种情况下,乳糖酶缺乏被认为是行为和如厕习惯发生急性变化的一个原因。很难评估ASD患者的疼痛,因此,提供者可能倾向于将新的行为归因于患者的发育差异。这个案例强调了调查非语言或发育迟缓的ASD儿童的多重疼痛伤亡的重要性。
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来源期刊
CiteScore
3.40
自引率
10.70%
发文量
140
审稿时长
24 days
期刊介绍: The Journal of Pediatric Health Care, the official journal of the National Association of Pediatric Nurse Practitioners, provides scholarly clinical information and research regarding primary, acute and specialty health care for children of newborn age through young adulthood within a family-centered context. The Journal disseminates multidisciplinary perspectives on evidence-based practice and emerging policy, advocacy and educational issues that are of importance to all healthcare professionals caring for children and their families.
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