The ocular frostbite involving cornea caused by low-temperature environment.

IF 1.7 4区医学 Q3 OPHTHALMOLOGY

BMC Ophthalmology Pub Date : 2025-10-03 DOI:10.1186/s12886-025-04390-4

Yue Yin, Lan Gong

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Abstract

Background: Corneal frostbite is a rarely reported condition, with unique pathophysiological characteristics distinct from classical frostbite of the extremities due to the cornea's specific anatomy and physiology.

Case presentation: We present a case of corneal frostbite caused by natural environmental exposure. Following a 3-hour marathon on ice at temperatures ranging from - 16 °C to -23 °C, the patient developed blurred vision in the right eye and bilateral photophobia with eye irritation. Clinical examination revealed stromal and endothelial edema of cornea in the right eye, with bilateral punctate corneal epithelial defects and conjunctival congestion. After 4 weeks of topical treatment, the patient's visual acuity and epithelial integrity were fully restored, though a permanent filiform endothelial scar remained.

Conclusions: Under the condition of corneal frostbite, the formation of ice crystals possibly directly damage both the epithelial and endothelial layers. This case report provides valuable insights for future research in ophthalmic emergency medicine.

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低温环境引起的累及角膜的眼部冻伤。

背景：角膜冻伤是一种很少报道的疾病，由于角膜特殊的解剖和生理特征，它具有独特的病理生理特征，与传统的四肢冻伤不同。病例介绍：我们报告一例角膜冻伤引起的自然环境暴露。在温度为- 16°C至-23°C的冰上马拉松3小时后，患者出现右眼视力模糊和双侧畏光并伴有眼睛刺激。临床检查显示右眼角膜间质及内皮水肿，双侧角膜点状上皮缺损，结膜充血。经过4周的局部治疗，患者的视力和上皮完整性完全恢复，但仍然存在永久性的丝状内皮疤痕。结论：在角膜冻伤条件下，冰晶的形成可能直接损伤角膜上皮和内皮层。本病例报告为今后眼科急诊医学的研究提供了有价值的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Ophthalmology OPHTHALMOLOGY-

CiteScore

3.40

自引率

5.00%

发文量

441

审稿时长

6-12 weeks

期刊介绍： BMC Ophthalmology is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of eye disorders, as well as related molecular genetics, pathophysiology, and epidemiology.