Postbiotics: what are they?

IF 3.1 4区医学 Q2 MICROBIOLOGY

Beneficial microbes Pub Date : 2025-10-02 DOI:10.1163/18762891-bja00103

M L Chikindas, L S Sichel, I V Popov, J R Tagg, X Lu, O V Mitrokhin, S D Todorov

引用次数: 0

Abstract

Although several internationally recognised scientific groups and non-governmental organisations have attempted to define 'postbiotics,' there remains no consensus. Leading experts have highlighted persistent problems of terminological inconsistency, lack of standardisation, and unclear boundaries between related concepts. What is needed is a comprehensive analysis that integrates existing definitions with considerations of manufacturing processes, mechanisms of action, and clinical applications. Ultimately, progress requires harmonisation of terminology to ensure comparability across studies and to provide a solid foundation for both academic and industry development.

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后生物：它们是什么？

尽管一些国际公认的科学团体和非政府组织试图定义“后生物”，但仍然没有达成共识。权威专家强调了术语不一致、缺乏标准化以及相关概念之间界限不清等长期存在的问题。我们需要的是一个综合分析，将现有的定义与生产工艺、作用机制和临床应用的考虑结合起来。最终，进步需要术语的统一，以确保研究之间的可比性，并为学术和行业发展提供坚实的基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Beneficial microbes MICROBIOLOGY-NUTRITION & DIETETICS

CiteScore

7.90

自引率

1.90%

发文量

审稿时长

>12 weeks

期刊介绍： Beneficial Microbes is a peer-reviewed scientific journal with a specific area of focus: the promotion of the science of microbes beneficial to the health and wellbeing of man and animal. The journal contains original research papers and critical reviews in all areas dealing with beneficial microbes in both the small and large intestine, together with opinions, a calendar of forthcoming beneficial microbes-related events and book reviews. The journal takes a multidisciplinary approach and focuses on a broad spectrum of issues, including safety aspects of pro- & prebiotics, regulatory aspects, mechanisms of action, health benefits for the host, optimal production processes, screening methods, (meta)genomics, proteomics and metabolomics, host and bacterial physiology, application, and role in health and disease in man and animal. Beneficial Microbes is intended to serve the needs of researchers and professionals from the scientific community and industry, as well as those of policy makers and regulators. The journal will have five major sections: * Food, nutrition and health * Animal nutrition * Processing and application * Regulatory & safety aspects * Medical & health applications In these sections, topics dealt with by Beneficial Microbes include: * Worldwide safety and regulatory issues * Human and animal nutrition and health effects * Latest discoveries in mechanistic studies and screening methods to unravel mode of action * Host physiology related to allergy, inflammation, obesity, etc. * Trends in application of (meta)genomics, proteomics and metabolomics * New developments in how processing optimizes pro- & prebiotics for application * Bacterial physiology related to health benefits