A rare ovarian tumor in childhood: Juvenile granulosa cell tumor revealed by pelvic pain and ovarian torsion

Q4 Medicine

Radiology Case Reports Pub Date : 2025-10-04 DOI:10.1016/j.radcr.2025.08.014

Karim Haddar MD, Hicham Benramdane MD, Leila Haddar MD, Hamid Ziani MD, Siham Nasri MD, PhD, Imane Kamaoui MD, PhD, Imane Skiker MD, PhD

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Abstract

We report the case of a 5-year-old girl admitted with a one-month history of pelvic heaviness and acute pelvic pain. Imaging revealed a large heterogeneous pelvic mass involving the genital compartment, with features suggestive of a malignant ovarian tumor. MRI demonstrated a 41 × 57 × 48 mm solid mass with heterogeneous enhancement, restricted diffusion, and areas of necrosis, infiltrating the recto-sigmoid junction. Tumor markers including AFP and beta-hCG were negative, while LDH was mildly elevated. Surgical exploration revealed an encapsulated left ovarian mass with 2 twists of the adnexa, prompting detorsion and partial oophorectomy. Histopathology confirmed a juvenile granulosa cell tumor. Postoperative recovery was uneventful. This case highlights the importance of considering JGCT in the differential diagnosis of ovarian masses in prepubertal girls, the value of advanced imaging for characterization and surgical planning, and the excellent prognosis associated with early surgical management.

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一例罕见的儿童期卵巢肿瘤：以骨盆疼痛和卵巢扭转为表现的幼年颗粒细胞瘤

我们报告的情况下，一个5岁的女孩承认一个月的历史盆腔沉重和急性盆腔疼痛。影像学显示一个大的不均匀盆腔肿块累及生殖隔室，特征提示恶性卵巢肿瘤。MRI示41 × 57 × 48 mm实性肿块，不均匀强化，扩散受限，坏死区域，浸润直乙状结肠交界处。肿瘤标志物包括甲胎蛋白和β - hcg均为阴性，而LDH轻度升高。手术探查发现左侧卵巢包被性肿块伴2个附件扭曲，提示卵巢部分切除。组织病理学证实为幼年颗粒细胞瘤。术后恢复顺利。本病例强调了在青春期前女孩卵巢肿块鉴别诊断中考虑JGCT的重要性，先进成像对特征和手术计划的价值，以及与早期手术治疗相关的良好预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiology Case Reports Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

1.10

自引率

0.00%

发文量

1074

审稿时长

30 days

期刊介绍： The content of this journal is exclusively case reports that feature diagnostic imaging. Categories in which case reports can be placed include the musculoskeletal system, spine, central nervous system, head and neck, cardiovascular, chest, gastrointestinal, genitourinary, multisystem, pediatric, emergency, women''s imaging, oncologic, normal variants, medical devices, foreign bodies, interventional radiology, nuclear medicine, molecular imaging, ultrasonography, imaging artifacts, forensic, anthropological, and medical-legal. Articles must be well-documented and include a review of the appropriate literature.