Magnetic sentinel node biopsy with Sienna+®/SentiMag® in penile squamous cell carcinoma: Case report

Abstract

Penile squamous cell carcinoma (SCC) is a rare malignancy where accurate nodal staging is essential for prognosis and management. Dynamic sentinel lymph node biopsy with radiotracers is the standard approach but requires nuclear medicine facilities and exposes patients to radiation. We report a 62-year-old man with penile SCC who underwent glansectomy with sentinel lymph node biopsy using Sienna+®/SentiMag® and methylene blue. Two sentinel nodes were identified, one exclusively by Sienna+®/SentiMag®. Both were negative for metastasis. This case supports the feasibility of magnetic tracers as a radiation-free alternative in penile cancer staging.