Statistical support for identification using epigenetic traits of the human skeleton

IF 2.5 3区 医学 Q1 MEDICINE, LEGAL
Shelby Scott, Tracy L. Rogers
{"title":"Statistical support for identification using epigenetic traits of the human skeleton","authors":"Shelby Scott,&nbsp;Tracy L. Rogers","doi":"10.1016/j.forsciint.2025.112673","DOIUrl":null,"url":null,"abstract":"<div><div>Radiologic comparison is a potentially reliable means of identification in forensic contexts. Most radiologic comparisons are subjective and involve a qualitative visual comparison of the degree of similarity between antemortem and postmortem images, which is insufficient for quantitatively assessing the evidentiary value of an identification. Rather than simply concluding that antemortem and postmortem radiologic comparisons appear the same in the opinion of the examiner, results should be expressed quantitatively. This bolsters conclusions by providing statistical support for the probability of correct identification. Epigenetic trait variation is assessed by a forensic anthropologist during the examination of unknown human skeletal remains and may be useful in establishing positive identification, and/or in providing investigative direction. A key factor in this regard is the frequency of the trait(s) being compared in a given population. The present study utilizes epigenetic trait data from a preceding publication to demonstrate a method of statistically quantifiable positive identification based on epigenetic trait frequencies, ultimately demonstrating the utility of this method in practice. Utilizing a case study approach, the present authors demonstrate the benefits of a combined likelihood approach and propose standards for the presentation of likelihood ratios and verbal equivalent statements, to promote consistency in the reporting of results.</div></div>","PeriodicalId":12341,"journal":{"name":"Forensic science international","volume":"378 ","pages":"Article 112673"},"PeriodicalIF":2.5000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic science international","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0379073825003172","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, LEGAL","Score":null,"Total":0}
引用次数: 0

Abstract

Radiologic comparison is a potentially reliable means of identification in forensic contexts. Most radiologic comparisons are subjective and involve a qualitative visual comparison of the degree of similarity between antemortem and postmortem images, which is insufficient for quantitatively assessing the evidentiary value of an identification. Rather than simply concluding that antemortem and postmortem radiologic comparisons appear the same in the opinion of the examiner, results should be expressed quantitatively. This bolsters conclusions by providing statistical support for the probability of correct identification. Epigenetic trait variation is assessed by a forensic anthropologist during the examination of unknown human skeletal remains and may be useful in establishing positive identification, and/or in providing investigative direction. A key factor in this regard is the frequency of the trait(s) being compared in a given population. The present study utilizes epigenetic trait data from a preceding publication to demonstrate a method of statistically quantifiable positive identification based on epigenetic trait frequencies, ultimately demonstrating the utility of this method in practice. Utilizing a case study approach, the present authors demonstrate the benefits of a combined likelihood approach and propose standards for the presentation of likelihood ratios and verbal equivalent statements, to promote consistency in the reporting of results.
利用人类骨骼的表观遗传特征进行鉴定的统计支持
在法医环境下,放射学比较是一种潜在可靠的鉴定手段。大多数放射学比较是主观的,涉及对死前和死后图像之间相似程度的定性视觉比较,这不足以定量评估鉴定的证据价值。而不是简单地得出结论,验尸官认为死前和死后的放射比较似乎是相同的,结果应该量化地表达。这通过为正确识别的概率提供统计支持来支持结论。表观遗传性状变异由法医人类学家在对未知人类骨骼遗骸进行检查时进行评估,可能有助于建立积极的鉴定,和/或提供调查方向。这方面的一个关键因素是在特定人群中比较性状的频率。本研究利用先前发表的表观遗传性状数据,展示了一种基于表观遗传性状频率的统计量化阳性鉴定方法,最终证明了该方法在实践中的实用性。利用案例研究方法,本文作者展示了组合似然方法的好处,并提出了似然比和口头等效陈述的呈现标准,以促进报告结果的一致性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Forensic science international
Forensic science international 医学-医学:法
CiteScore
5.00
自引率
9.10%
发文量
285
审稿时长
49 days
期刊介绍: Forensic Science International is the flagship journal in the prestigious Forensic Science International family, publishing the most innovative, cutting-edge, and influential contributions across the forensic sciences. Fields include: forensic pathology and histochemistry, chemistry, biochemistry and toxicology, biology, serology, odontology, psychiatry, anthropology, digital forensics, the physical sciences, firearms, and document examination, as well as investigations of value to public health in its broadest sense, and the important marginal area where science and medicine interact with the law. The journal publishes: Case Reports Commentaries Letters to the Editor Original Research Papers (Regular Papers) Rapid Communications Review Articles Technical Notes.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信