Composites-based electrodes in enzymatic electrochemical glucose biosensors

IF 4.1 3区化学 Q1 CHEMISTRY, ANALYTICAL

Journal of Electroanalytical Chemistry Pub Date : 2025-09-27 DOI:10.1016/j.jelechem.2025.119505

Antanas Zinovicius , Evaldas Balciunas , Juste Rozene , Jurate Jolanta Petroniene , Agne Bogusevice , Kosuke Ino , Laisvidas Striska , Tomas Mockaitis , Inga Morkvenaite

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引用次数: 0

Abstract

Glucose imbalance in the human body is associated with multiple metabolic conditions such as hypoglycemia, hyperglycemia, insulin resistance, hyperinsulinemia, and diabetes. This review examines the latest developments in enzymatic glucose biosensors, with a focus on those utilizing nanocomposites and polymers. Conductive polymers, carbon nanostructures, metal nanoparticles, polymers with embedded metal nanoparticles, and polymeric ionic liquid-based structures are the most convenient for the design of electrochemical biosensors. Conductive polymer materials enhance electron transfer, improve biocompatibility, and enable flexible biosensor designs. Carbon nanostructures can be integrated with polymeric materials, improving the charge transfer. Polymer-metal structure-containing electrodes improve glucose sensor performance by enhancing conductivity and stability. Complex composite-based electrodes enable the exploitation of combinations of benefits provided by all previously mentioned materials. Significant progress in sensor performance was achieved by tailoring the composition and structure of these components.

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复合材料电极在酶促电化学葡萄糖生物传感器中的应用

人体葡萄糖失衡与多种代谢状况有关，如低血糖、高血糖、胰岛素抵抗、高胰岛素血症和糖尿病。本文综述了酶促葡萄糖生物传感器的最新进展，重点介绍了利用纳米复合材料和聚合物的生物传感器。导电聚合物、碳纳米结构、金属纳米粒子、嵌入金属纳米粒子的聚合物和聚合物离子液体基结构是设计电化学生物传感器最方便的材料。导电聚合物材料增强电子传递，改善生物相容性，并使灵活的生物传感器设计成为可能。碳纳米结构可以与高分子材料集成，改善电荷转移。含有聚合物金属结构的电极通过提高导电性和稳定性来改善葡萄糖传感器的性能。复杂的基于复合材料的电极可以利用所有前面提到的材料所提供的优点的组合。通过定制这些组件的组成和结构，传感器性能取得了重大进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Electroanalytical Chemistry 化学-电化学

CiteScore

7.80

自引率

6.70%

发文量

912

审稿时长

2.4 months

期刊介绍： The Journal of Electroanalytical Chemistry is the foremost international journal devoted to the interdisciplinary subject of electrochemistry in all its aspects, theoretical as well as applied. Electrochemistry is a wide ranging area that is in a state of continuous evolution. Rather than compiling a long list of topics covered by the Journal, the editors would like to draw particular attention to the key issues of novelty, topicality and quality. Papers should present new and interesting electrochemical science in a way that is accessible to the reader. The presentation and discussion should be at a level that is consistent with the international status of the Journal. Reports describing the application of well-established techniques to problems that are essentially technical will not be accepted. Similarly, papers that report observations but fail to provide adequate interpretation will be rejected by the Editors. Papers dealing with technical electrochemistry should be submitted to other specialist journals unless the authors can show that their work provides substantially new insights into electrochemical processes.