{"title":"Advanced ferrite hybrid nanostructures for electrochemical sensing: a review of biomedical diagnostic applications","authors":"Murat Çelik , Ipek Kucuk , Selenay Sadak , Bengi Uslu","doi":"10.1016/j.microc.2025.115507","DOIUrl":null,"url":null,"abstract":"<div><div>Ferrite hybrid structures are compounds classified as magnetic metal oxides, often denoted by the formula MFe₂O₄. M usually refers to divalent metal ions, including Mn, Fe, Co, Ni, Cu or Zn. Hybrid nanostructures provide both high conductivity and large surface area, offering more sensitive and reliable sensing in electrochemical sensors. The physical and chemical properties of ferrihybrids vary depending on synthesis methods and processing conditions. Recently, ferrihybrid materials have come to the forefront with their catalytic and magnetic properties and are widely preferred for their ability to increase the selectivity and sensitivity of the developed sensor. The application of ferri-hybrid nanosensors in diagnostics is examined in this comprehensive review under four main headings: cancer, neurodegenerative, renal and diabetes mellitus diseases. Under these headings, metals that form a hybrid structure with ferrite are examined, the synthesis of these structures is reviewed and the reasons for their preference in electrochemical diagnosis are investigated and organized in tables.</div></div>","PeriodicalId":391,"journal":{"name":"Microchemical Journal","volume":"218 ","pages":"Article 115507"},"PeriodicalIF":4.9000,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchemical Journal","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0026265X25028553","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Ferrite hybrid structures are compounds classified as magnetic metal oxides, often denoted by the formula MFe₂O₄. M usually refers to divalent metal ions, including Mn, Fe, Co, Ni, Cu or Zn. Hybrid nanostructures provide both high conductivity and large surface area, offering more sensitive and reliable sensing in electrochemical sensors. The physical and chemical properties of ferrihybrids vary depending on synthesis methods and processing conditions. Recently, ferrihybrid materials have come to the forefront with their catalytic and magnetic properties and are widely preferred for their ability to increase the selectivity and sensitivity of the developed sensor. The application of ferri-hybrid nanosensors in diagnostics is examined in this comprehensive review under four main headings: cancer, neurodegenerative, renal and diabetes mellitus diseases. Under these headings, metals that form a hybrid structure with ferrite are examined, the synthesis of these structures is reviewed and the reasons for their preference in electrochemical diagnosis are investigated and organized in tables.
期刊介绍:
The Microchemical Journal is a peer reviewed journal devoted to all aspects and phases of analytical chemistry and chemical analysis. The Microchemical Journal publishes articles which are at the forefront of modern analytical chemistry and cover innovations in the techniques to the finest possible limits. This includes fundamental aspects, instrumentation, new developments, innovative and novel methods and applications including environmental and clinical field.
Traditional classical analytical methods such as spectrophotometry and titrimetry as well as established instrumentation methods such as flame and graphite furnace atomic absorption spectrometry, gas chromatography, and modified glassy or carbon electrode electrochemical methods will be considered, provided they show significant improvements and novelty compared to the established methods.