Occupational exposure to extremely low-frequency magnetic fields (ELF-MF) and postmenopausal breast cancer risk.

IF 1.4
Saeedeh Moayedi-Nia, Chelsea Almadin, France Labrèche, Mark S Goldberg, Lesley Richardson, Elisabeth Cardis, Vikki Ho
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引用次数: 0

Abstract

Objective: Estimate the association between occupational exposures to extremely low-frequency magnetic fields (ELF-MF) and postmenopausal breast cancer.

Methods: Lifetime job histories from a population-based case-control study (2008-2011) of histologically-confirmed breast cancer in Montréal, Canada were linked to a job-exposure matrix to assign geometric mean ELF-MF exposure/workday. Logistic regression estimated odds ratios (OR) and 95% confidence intervals (CI) for cumulative, average, maximum, and duration of maximum exposure to ELF-MF (per interquartile range increase), adjusting for individual-level and ecological covariables.

Results: Data from 663 cases and 592 controls revealed no association between occupational ELF-MF exposure and postmenopausal breast cancer, though restricting exposures to 0-10 years before interview and to those during breast development, some positive associations was observed, particularly for ER+/PR+ tumours.

Conclusions: Our findings suggest no association between occupational ELF-MF exposure and postmenopausal breast cancer risk.

职业接触极低频磁场(ELF-MF)与绝经后乳腺癌风险
目的:评估职业暴露于极低频磁场(ELF-MF)与绝经后乳腺癌之间的关系。方法:在加拿大montracimal的一项以人群为基础的病例对照研究(2008-2011)中,组织学证实的乳腺癌患者的一生工作经历与工作暴露矩阵相关联,以确定几何平均ELF-MF暴露/工作日。Logistic回归估计了累积、平均、最大和最大暴露于ELF-MF的持续时间(每四分位数范围增加)的比值比(OR)和95%置信区间(CI),并调整了个人水平和生态协变量。结果:来自663例病例和592例对照的数据显示,职业性ELF-MF暴露与绝经后乳腺癌之间没有关联,尽管将暴露限制在访谈前0-10年以及乳房发育期间,但观察到一些正相关,特别是对于ER+/PR+肿瘤。结论:我们的研究结果表明职业性ELF-MF暴露与绝经后乳腺癌风险之间没有关联。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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