Longitudinal associations between household use of "green" cleaning products and asthma symptoms.

IF 6.6 1区医学 Q1 ALLERGY

Journal of Allergy and Clinical Immunology-In Practice Pub Date : 2025-09-30 DOI:10.1016/j.jaip.2025.09.027

Emilie Pacheco Da Silva, Raphaëlle Varraso, Léopold K Fezeu, Pilar Galan, Serge Hercberg, Mathilde Touvier, Christophe Paris, Nicole Le Moual, Orianne Dumas

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引用次数: 0

Abstract

Background: The household use of irritant and sprayed cleaning products is an established asthma risk factor, which could motivate consumers to turn to "green" products. However, only two cross-sectional studies, with inconsistent results, evaluated the potential respiratory health impacts of "green" products.

Objective: We investigated 2-years effects on asthma of household use of "green" products and irritants/sprays, using longitudinal data from the French NutriNet-Santé cohort.

Methods: The asthma symptom score and household use of "green" products and irritants/sprays were evaluated using standardized questionnaires in 2018 and 2020. The evolution of weekly use (persistent, increased versus no weekly use) was studied in association with (i) the asthma symptom score in 2020; (ii) the incidence of asthma symptoms between 2018-2020 (incidence vs. asymptomatic); (iii) the evolution of asthma symptoms between 2018-2020 (improvement, deterioration vs. symptomatic stable) by logistic regressions. Models were adjusted for sex, age, smoking status, body mass index, educational level, and use of irritants/sprays (for "green" products).

Results: Our study was based on 30,012 adults (mean age: 49 years(sd:14), 74% women). For irritants/sprays, a persistent (40%) and an increased (26%) use was associated with asthma symptoms (Mean Score Ratio(MSR)=1.26[1.18-1.34] & MSR=1.14[1.06-1.22], respectively), incidence (OR=1.30[1.16-1.45] & OR=1.07[0.95-1.20]), and deterioration (OR=1.48[1.19-1.85] & OR=1.28[1.01-1.64]). For green products, a persistent (20%) and an increased (12%) use was associated with symptoms in 2020 (MSR=1.08[1.01-1.16] & MSR=1.07[0.99-1.16]), and associations were suggested with incidence (OR=1.09[0.97-1.22] & OR=1.11[0.97-1.27]).

Conclusion: Persistent and increased use of irritants/sprays but also "green" products was associated with deleterious effects on asthma over time.

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家庭使用“绿色”清洁产品与哮喘症状之间的纵向关联。

背景：家庭使用刺激性和喷雾清洁产品是一个确定的哮喘风险因素，这可能促使消费者转向“绿色”产品。然而，只有两项横断面研究评估了“绿色”产品对呼吸系统健康的潜在影响，结果不一致。目的：我们研究了家庭使用“绿色”产品和刺激物/喷雾剂对哮喘的2年影响，使用来自法国nutrinet - sant队列的纵向数据。方法：采用标准化问卷对2018年和2020年哮喘症状评分和家庭“绿色”产品和刺激物/喷雾剂的使用情况进行评估。研究了每周用药的演变（持续、增加或不使用）与(i) 2020年哮喘症状评分的关系；（ii） 2018-2020年间哮喘症状的发生率（发病率与无症状）；（iii）通过logistic回归分析2018-2020年间哮喘症状的演变（改善、恶化vs症状稳定）。根据性别、年龄、吸烟状况、体重指数、教育水平和使用刺激物/喷雾剂（“绿色”产品）对模型进行了调整。结果：我们的研究基于30,012名成年人（平均年龄：49岁（sd:14）， 74%为女性）。对于刺激物/喷雾剂，持续（40%）和增加（26%）使用与哮喘症状相关（平均评分比（MSR）分别为1.26[1.18-1.34]和MSR=1.14[1.06-1.22]）、发病率（OR=1.30[1.16-1.45]和OR=1.07[0.95-1.20]）和恶化（OR=1.48[1.19-1.85]和OR=1.28[1.01-1.64]）。对于绿色产品，持续（20%）和增加（12%）的使用与2020年的症状相关（MSR=1.08[1.01-1.16]和MSR=1.07[0.99-1.16]），并且与发病率相关（OR=1.09[0.97-1.22]和OR=1.11[0.97-1.27]）。结论：随着时间的推移，持续和增加使用刺激物/喷雾剂以及“绿色”产品与哮喘的有害影响有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Allergy and Clinical Immunology-In Practice ALLERGYIMMUNOLOGY-IMMUNOLOGY

CiteScore

11.10

自引率

9.60%

发文量

683

审稿时长

50 days

期刊介绍： JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.