From microscopic haematuria to kidney failure: The hidden progression of IgA nephropathy.

IF 1.7 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Shriram Swaminathan, Bobby Chacko
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引用次数: 0

Abstract

Background: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis and a leading cause of chronic kidney disease globally. IgAN often presents with varied symptoms, and general practitioners (GPs) play a key role in its early detection and management.

Objective: This review aims to provide GPs with an overview of IgAN, focusing on clinical presentations that warrant referral to nephrology and highlighting common pitfalls in primary care management with a case example.

Discussion: Recognising high-risk features of IgAN through symptoms such as haematuria or proteinuria, addressing modifiable factors and understanding recent advances in management are vital for improving patient outcomes. New therapies targeting pathogenic pathways underscore the importance of collaborative care.

从显微镜下血尿到肾衰竭:IgA肾病的隐性进展。
背景:免疫球蛋白A肾病(IgAN)是最常见的原发性肾小球肾炎,也是全球慢性肾脏疾病的主要原因。IgAN通常表现为多种症状,全科医生(gp)在其早期发现和管理中发挥关键作用。目的:本综述旨在为全科医生提供IgAN的概述,重点关注临床表现,保证转诊到肾脏病学,并通过一个案例强调初级保健管理中的常见缺陷。讨论:通过血尿或蛋白尿等症状认识IgAN的高危特征,解决可改变的因素并了解治疗的最新进展对于改善患者预后至关重要。针对致病途径的新疗法强调了协作治疗的重要性。
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来源期刊
Australian Journal of General Practice
Australian Journal of General Practice Medicine-Family Practice
CiteScore
2.80
自引率
4.50%
发文量
284
期刊介绍: The Australian Journal of General Practice (AJGP) aims to provide relevant, evidence-based, clearly articulated information to Australian general practitioners (GPs) to assist them in providing the highest quality patient care, applicable to the varied geographic and social contexts in which GPs work and to all GP roles as clinician, researcher, educator, practice team member and opinion leader. All articles are subject to peer review before they are accepted for publication.
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