Obliteration of the Epitympanum and Mastoid Results in Reduced Cholesteatoma Recidivism: Long-term Outcomes and Technique.

IF 2 3区 医学 Q3 CLINICAL NEUROLOGY
Simon I Angeli, Stefania Goncalves, Juan A Chiossone-Kerdel
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引用次数: 0

Abstract

Objective: To compare long-term rates of cholesteatoma recidivism between cases undergoing tympanomastoidectomy with obliteration and without obliteration.

Study design: Retrospective case-control.

Setting: Tertiary referral center.

Patients: Adults and older children with pars flaccida cholesteatoma.

Intervention: Tympanomastoidectomy with or without obliteration of the epitympanum and mastoid.

Main outcome measure: Recidivistic cholesteatoma (ie, residual and/or recurrent cholesteatoma) determined by otoscopy, revision surgery, or imaging.

Methods: Retrospective chart review of pars flaccida cholesteatoma surgeries by a single surgeon between 2015 and 2023. Demographic, clinical, and surgical information, inclusive of cholesteatoma type and EAONO/JOS staging.

Results: There were 60 cases with obliteration and 63 cases without obliteration that were similar in age, sex, hearing, and cholesteatoma type and stage. Cases with obliteration had statistically significantly lower rates of recurrent (5% vs. 17%, P=0.0447) and residual (3.3% vs. 16%, P=0.0303) cholesteatoma compared with those without obliteration. The overall rate of recidivistic disease was 23.8% in cases without obliteration and 6.8% in cases with obliteration (P=0.0116). Using Kaplan-Meier analysis, recidivistic cholesteatoma-free survival rates at 5 years for the obliteration and non-obliteration groups were 91% and 63%, respectively (P=0.0367, log-rank test). No other clinical or surgical factors influenced recidivism.

Conclusions: Epitympanum and mastoid obliteration during CWU and CWD tympanomastoidectomy for pars flaccida cholesteatoma is associated with reduced rates of recurrent and residual disease when compared with cases without obliteration.

上腔和乳突闭塞减少胆脂瘤再犯:长期结果和技术。
目的:比较胆脂瘤鼓室瘤切除术合并和不合并的远期再犯率。研究设计:回顾性病例对照。单位:三级转诊中心。患者:成人和年龄较大的儿童松弛部胆脂瘤。干预:鼓室乳突切除伴或不伴上鼓室和乳突闭塞。主要结局指标:复发性胆脂瘤(即残留和/或复发性胆脂瘤)由耳镜检查、翻修手术或影像学检查确定。方法:回顾性分析2015年至2023年单一外科医生手术的松弛部胆脂瘤病例。人口统计学、临床和手术信息,包括胆脂瘤类型和EAONO/JOS分期。结果:年龄、性别、听力、胆脂瘤分型、分期相近,有湮没者60例,无湮没者63例。与未闭塞组相比,闭塞组的复发率(5%比17%,P=0.0447)和残留率(3.3%比16%,P=0.0303)具有统计学意义。未闭塞者复发率为23.8%,闭塞者复发率为6.8% (P=0.0116)。Kaplan-Meier分析显示,闭塞组和非闭塞组5年无复发性胆脂瘤生存率分别为91%和63% (P=0.0367, log-rank检验)。没有其他临床或手术因素影响累犯。结论:在CWU和CWD鼓室乳突瘤切除术中,与未切除鼓室乳突瘤的病例相比,上鼓室乳突瘤的复发和残留率降低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Otology & Neurotology
Otology & Neurotology 医学-耳鼻喉科学
CiteScore
3.80
自引率
14.30%
发文量
509
审稿时长
3-6 weeks
期刊介绍: ​​​​​Otology & Neurotology publishes original articles relating to both clinical and basic science aspects of otology, neurotology, and cranial base surgery. As the foremost journal in its field, it has become the favored place for publishing the best of new science relating to the human ear and its diseases. The broadly international character of its contributing authors, editorial board, and readership provides the Journal its decidedly global perspective.
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