[Retracted] MicroRNA‑363‑3p is downregulated in hepatocellular carcinoma and inhibits tumorigenesis by directly targeting specificity protein 1.

IF 3.5 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL
Molecular medicine reports Pub Date : 2025-12-01 Epub Date: 2025-10-03 DOI:10.3892/mmr.2025.13699
Jie Ying, Xuechun Yu, Chaojian Ma, Yongqi Zhang, Jingwu Dong
{"title":"[Retracted] MicroRNA‑363‑3p is downregulated in hepatocellular carcinoma and inhibits tumorigenesis by directly targeting specificity protein 1.","authors":"Jie Ying, Xuechun Yu, Chaojian Ma, Yongqi Zhang, Jingwu Dong","doi":"10.3892/mmr.2025.13699","DOIUrl":null,"url":null,"abstract":"<p><p>Following the publication of this paper, it was drawn to the Editor's attention by a reader that, regarding the Transwell assay data shown in Fig 5, there was a slight concern that the data panels showing the results for the migration and invasion assay experiments for the two investigated cell lines (Hep3B and SMMC‑7721) may have respectively originated from the same photos. Moreover, the 'Hep3B/Migration/miR‑363‑3p mimics + pcDNA3.1‑Sp1' and SMMC‑67721/Invasion/miR‑363‑3p mimics + pcDNA3.1‑Sp1' data panels contained an area of overlapping data, such that data which were intended to show the results from differently performed experiments had apparently been derived from the same original source. A subsequent analysis of the data in this paper revealed that there were a number of internal data duplications comparing Figs. 2C and 5 in this paper, and certain of these data had already been submitted for publication in an article written by different authors at different research institutes to the journal Oncology Letters. In view of the fact that the abovementioned data had already been submitted for publication before this paper was submitted to <i>Molecular Medicine Reports</i>, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply.. The Editor apologizes to the readership for any inconvenience caused. [Molecular Medicine Reports 16: 1603‑1611, 2017; DOI: 10.3892/mmr.2017.6759].</p>","PeriodicalId":18818,"journal":{"name":"Molecular medicine reports","volume":"32 6","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Molecular medicine reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3892/mmr.2025.13699","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/10/3 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by a reader that, regarding the Transwell assay data shown in Fig 5, there was a slight concern that the data panels showing the results for the migration and invasion assay experiments for the two investigated cell lines (Hep3B and SMMC‑7721) may have respectively originated from the same photos. Moreover, the 'Hep3B/Migration/miR‑363‑3p mimics + pcDNA3.1‑Sp1' and SMMC‑67721/Invasion/miR‑363‑3p mimics + pcDNA3.1‑Sp1' data panels contained an area of overlapping data, such that data which were intended to show the results from differently performed experiments had apparently been derived from the same original source. A subsequent analysis of the data in this paper revealed that there were a number of internal data duplications comparing Figs. 2C and 5 in this paper, and certain of these data had already been submitted for publication in an article written by different authors at different research institutes to the journal Oncology Letters. In view of the fact that the abovementioned data had already been submitted for publication before this paper was submitted to Molecular Medicine Reports, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply.. The Editor apologizes to the readership for any inconvenience caused. [Molecular Medicine Reports 16: 1603‑1611, 2017; DOI: 10.3892/mmr.2017.6759].

【撤回】MicroRNA‑363‑3p在肝细胞癌中下调,通过直接靶向特异性蛋白1抑制肿瘤发生。
在这篇论文发表后,一位读者引起了编辑的注意,关于图5所示的Transwell实验数据,有人稍微担心显示两种研究细胞系(Hep3B和SMMC - 7721)迁移和侵袭实验结果的数据面板可能分别来自同一张照片。此外,“Hep3B/Migration/miR‑363‑3p mimics + pcDNA3.1‑Sp1”和SMMC‑67721/Invasion/miR‑363‑3p mimics + pcDNA3.1‑Sp1”数据面板包含重叠数据区域,因此,旨在显示不同实验结果的数据显然来自相同的原始来源。随后对本文数据的分析发现,对比图2C和图5,存在大量的内部数据重复,其中一些数据已经由不同研究机构的不同作者提交给《肿瘤学快报》杂志发表。鉴于上述数据在本文提交给Molecular Medicine Reports之前已经提交发表,编辑决定从该期刊撤回本文。作者被要求对这些担忧作出解释,但编辑部没有收到答复。对于由此给读者带来的不便,本刊编辑深表歉意。[分子医学报告]16:1603‑1611,2017;DOI: 10.3892 / mmr.2017.6759]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Molecular medicine reports
Molecular medicine reports 医学-病理学
CiteScore
7.60
自引率
0.00%
发文量
321
审稿时长
1.5 months
期刊介绍: Molecular Medicine Reports is a monthly, peer-reviewed journal available in print and online, that includes studies devoted to molecular medicine, underscoring aspects including pharmacology, pathology, genetics, neurosciences, infectious diseases, molecular cardiology and molecular surgery. In vitro and in vivo studies of experimental model systems pertaining to the mechanisms of a variety of diseases offer researchers the necessary tools and knowledge with which to aid the diagnosis and treatment of human diseases.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信