Reproducibility of fNIRS within subject for visual and motor tasks

IF 4.5 2区医学 Q1 NEUROIMAGING

NeuroImage Pub Date : 2025-09-30 DOI:10.1016/j.neuroimage.2025.121492

Julie C. Wagner , Anthony Zinos , Scott A. Beardsley , Wei-Liang Chen , Lisa Conant , Marsha Malloy , Joseph Heffernan , Brendan Quirk , Robert Prost , Mohit Maheshwari , Jeffrey Sugar , Harry T. Whelan

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引用次数: 0

Abstract

Functional Near Infrared Spectroscopy (fNIRS) is becoming a popular metric to noninvasively identify brain activity through assessing changes in oxygenated (HbO) and deoxygenated (HbR) hemoglobin concentration. Several aspects of fNIRS imaging are appealing for clinical applications but the reproducibility of fNIRS signals has yet to be determined over several sessions. To address this, four participants completed at least ten sessions on separate days where they performed Motor and Visual tasks while fNIRS signals were measured from 102 channels spanning the entire head. Reproducibility was quantified as the percentage of significant task related activity occurring across sessions at the channel and source levels (anatomically specific and default head models) via Region of Interest (ROI) and vertex-wise analyses. To improve source localization, digitized optode positions from each session were used with the anatomy specific source localization. Individual differences in reproducibility were present yet task-related changes in HbO were significantly more reproducible over sessions than changes in HbR (F(1, 66) = 5.03, p < 0.05). Increased shifts in optode position correlated with less spatial overlap across sessions for each participant. Further steps can be taken to increase the reliability of capturing brain activity with fNIRS by improving upon data acquisition and analysis techniques.

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近红外光谱在受试者视觉和运动任务中的再现性。

功能近红外光谱（fNIRS）通过评估氧合（HbO）和脱氧（HbR）血红蛋白浓度的变化，成为一种无创识别大脑活动的流行指标。fNIRS成像的几个方面对临床应用很有吸引力，但fNIRS信号的可重复性尚未在几次会议上确定。为了解决这个问题，四名参与者在不同的日子里完成了至少十次的运动和视觉任务，同时测量了横跨整个头部的102个通道的近红外光谱信号。通过感兴趣区域（ROI）和顶点分析，可重复性被量化为在通道和源级别（解剖特异性和默认头部模型）的会话中发生的重要任务相关活动的百分比。为了提高源定位，每个会话的数字化光电位置与解剖特定的源定位一起使用。可重复性存在个体差异，但HbO的任务相关变化在会话期间的可重复性显著高于HbR的变化(F（1,66） = 5.03,p

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来源期刊

NeuroImage 医学-核医学

CiteScore

11.30

自引率

10.50%

发文量

809

审稿时长

63 days

期刊介绍： NeuroImage, a Journal of Brain Function provides a vehicle for communicating important advances in acquiring, analyzing, and modelling neuroimaging data and in applying these techniques to the study of structure-function and brain-behavior relationships. Though the emphasis is on the macroscopic level of human brain organization, meso-and microscopic neuroimaging across all species will be considered if informative for understanding the aforementioned relationships.